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iScale Oligos DNA are milligram and gram quantities of custom DNA oligonucleotides manufactured to meet specialized needs for in vivo, high-throughput, and commercial projects including research tools, molecular diagnostics, and laboratory developed tests (LDT).

Order

For anything marked as ‘Inquire’ above or if you have needs that are different from the other general specifications presented, please send a request to dnaoligos@milliporesigma.com.
For iScale quantities of NGS adapters, please see our Next-Gen Sequencing Oligos products.

Useful Applications

  • Antisense
  • Binding studies
  • High-throughput PCR/qPCR
  • Sanger Sequencing & NGS (non-adapters)
  • X-ray crystallographic structure determination
  • Immunostimulatory assays
  • Microarray production

Quality Assurance

At the foundation of our manufacturing processes is a robust Quality Management System (QMS), which drives compliance to our following Quality Registrations:

  • ISO 9001:2015 for manufacturing research-grade oligonucleotides
  • ISO 13485:2016 for manufacturing diagnostic-grade oligonucleotides
  • ISO 14001:2015 for effective environmental management

This quality culture is integrated into all aspects of our business. Key components of our QMS include:

  • Certificates of analysis
  • Document control
  • Change notification
  • Vendor management
  • Business agreements
  • Corrective and preventive actions

Each component drives quality assurance, and for verification, we routinely host rigorous registrar, internal, and customer audits.

Related Product Categories
Custom & Predesigned DNA Oligos and qPCR Probes
Discover our custom DNA oligos portfolio including primers, qPCR probes, high-throughput DNA in plates, and next-generation sequencing (NGS) adapters available in multiple formats that comply with ISO 9001 and ISO 13485 quality systems for research and commercial applications.
PCR Reagents & Kits
Polymerase Chain Reaction (PCR) is a mainstay in molecular biology labs. PCR is used for amplifying DNA by several orders of magnitude and our reagents and resources are suitable for numerous research workflows including, gene expression analysis, genotyping, sequencing, and mutagenesis application needs.
Predesigned siRNA
We offer advanced design and quality synthesis for predesigned siRNA and siRNA libraries using the Rosetta siRNA Design Algorithm to reduce off-target effects and increase RNAi performance. The algorithm utilizes Position-Specific Scoring Matrices (PSSM) and knowledge of the siRNA seed region to predict the most effective and specific siRNA sequences for a target gene of interest.
Related Applications
PCR Applications
Polymerase chain reaction (PCR) is a technique for amplifying nucleic acid molecules and is commonly used in many applications, including RT-PCR, hot start PCR, end point PCR and more.
qPCR
Quantitative PCR (qPCR) or quantitative Real-Time PCR applications, utilizing fluorescent report molecules, suitable for your microRNA, genotyping, and gene expression analyses.
Next Gen Sequencing
Next-Generation Sequencing (NGS) reagents and resources for massively parallel sequencing applications.
Gene Expression & Silencing
CRISPR, miRNA, siRNA, and shRNA technologies for gene expression and gene silencing applications.
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