CLDN14
claudin 14
Synonyms:
DFNB29
Species:
Human CLDN14 (23562), Mouse Cldn14 (56173), Rat Cldn14 (304073), domestic cat CLDN14 (101082083), chicken CLDN14 (427982), domestic guinea pig Cldn14 (100726532), naked mole-rat Cldn14 (101724744), cow CLDN14 (783180), sheep CLDN14 (101109068), dog CLDN14 (487751)
UniProtKB ID:
Gene ID:
- Human(23562) Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]
- Mouse(56173) claudin 14
- Rat(304073) claudin 14
- domestic cat(101082083) claudin 14
- chicken(427982) claudin 14
- domestic guinea pig(100726532) claudin 14
- naked mole-rat(101724744) claudin 14
- cow(783180) claudin 14
- sheep(101109068) claudin 14
- dog(487751) claudin 14
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CLDN14 antibody produced in mouse, clone 3D11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
immunoprecipitation (IP)
esiRNA
Product Number
Description
Species