Skip to Content
Merck
CN

CTPS2

CTP synthase 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(56474) Summary: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jan 2009]
  • Mouse(55936) cytidine 5'-triphosphate synthase 2
  • Rat(619580) CTP synthase 2
  • domestic guinea pig(100731157) CTP synthase 2
  • naked mole-rat(101704664) CTP synthase 2
  • sheep(101105631) CTP synthase 2
  • domestic cat(101097209) CTP synthase 2
  • cow(767849) CTP synthase II
  • dog(480851) CTP synthase 2
  • chicken(418620) CTP synthase II

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CTPS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CTPS2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CTPS2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
western blot
Anti-CTPS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
ANTI-CTPS2 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CTPS2,
Species
human
MISSION® esiRNA, targeting mouse Ctps2,
Species
mouse