CYTH1
cytohesin 1
Synonyms:
B2-1, CYTOHESIN-1, D17S811E, PSCD1, SEC7
Species:
Human CYTH1 (9267), Mouse Cyth1 (19157), Rat Cyth1 (116691), chicken CYTH1 (422085), domestic guinea pig Cyth1 (100725624), naked mole-rat Cyth1 (101705470), sheep CYTH1 (101112995), cow CYTH1 (100141038), Horse CYTH1 (100057600), dog CYTH1 (608079)
UniProtKB ID:
Gene ID:
- Human(9267) Summary: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2. [provided by RefSeq, Aug 2008]
- Mouse(19157) cytohesin 1
- Rat(116691) cytohesin 1
- chicken(422085) cytohesin 1
- domestic guinea pig(100725624) cytohesin 1
- naked mole-rat(101705470) cytohesin 1
- sheep(101112995) cytohesin 1
- cow(100141038) cytohesin 1
- Horse(100057600) cytohesin 1
- dog(608079) cytohesin 1
- domestic cat(101082609) cytohesin 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PSCD1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-PSCD1 antibody produced in mouse, clone 1D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot