FBXO22
F-box protein 22
Synonyms:
FBX22, FISTC1
Species:
Human FBXO22 (26263), Mouse Fbxo22 (71999), Rat Fbxo22 (300724), domestic cat FBXO22 (101094853), sheep FBXO22 (101102339), cow FBXO22 (536605), naked mole-rat Fbxo22 (101697256), domestic guinea pig Fbxo22 (100731256), chicken FBXO22 (415355), Zebrafish fbxo22 (556909) ...More
UniProtKB ID:
Gene ID:
- Human(26263) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]
- Mouse(71999) F-box protein 22
- Rat(300724) F-box protein 22
- domestic cat(101094853) F-box protein 22
- sheep(101102339) F-box protein 22
- cow(536605) F-box protein 22
- naked mole-rat(101697256) F-box protein 22
- domestic guinea pig(100731256) F-box protein 22
- chicken(415355) F-box protein 22
- Zebrafish(556909) F-box protein 22
- Horse(100050726) F-box protein 22
- dog(487672) F-box protein 22
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-FBXO22 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, horse, human, rat
Application
western blot