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FBXO8

F-box protein 8

Synonyms:
FBS, FBX8
Species:
UniProtKB ID:
Gene ID:
  • Human(26269) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008]
  • Mouse(50753) F-box protein 8
  • Rat(306436) F-box protein 8
  • naked mole-rat(101713357) F-box protein 8
  • domestic guinea pig(100726283) F-box protein 8
  • domestic cat(101088075) F-box protein 8
  • cow(538528) F-box protein 8
  • chicken(422565) F-box protein 8
  • Domestic Rabbit(100358150) F-box protein 8
  • dog(477359) F-box protein 8
  • Horse(100061095) F-box protein 8
  • Zebrafish(678549) F-box protein 8
  • sheep(101119879) F-box protein 8

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FBXO8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Monoclonal Anti-FBXO8 antibody produced in mouse, clone 1C11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-FBXO8 antibody produced in mouse, clone 2F11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Fbxo8,
Species
mouse
MISSION® esiRNA, targeting human FBXO8,
Species
human
MISSION® esiRNA, targeting mouse Fbxo8,
Species
mouse