Merck
CN

GRIK1

glutamate receptor, ionotropic, kainate 1

Synonyms:
EAA3, EEA3, GLR5, GLUR5, GluK1
Species:
Human GRIK1 (2897), Mouse Grik1 (14805), Rat Grik1 (29559), naked mole-rat Grik1 (101705989), dog GRIK1 (487719), chicken GRIK1 (418489), Thale Cress GRIK1 (823660), cow GRIK1 (533760), domestic cat GRIK1 (101097165), Horse GRIK1 (100053602) ...More
UniProtKB ID:
P39086, Q13001, Q86SU9
Gene ID:
  • Human(2897) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14805) glutamate receptor, ionotropic, kainate 1
  • Rat(29559) glutamate receptor, ionotropic, kainate 1
  • naked mole-rat(101705989) glutamate receptor, ionotropic, kainate 1
  • dog(487719) glutamate receptor, ionotropic, kainate 1
  • chicken(418489) glutamate receptor, ionotropic, kainate 1
  • Thale Cress(823660) serine/threonine-protein kinase GRIK1
  • cow(533760) glutamate receptor, ionotropic, kainate 1
  • domestic cat(101097165) glutamate receptor, ionotropic, kainate 1
  • Horse(100053602) glutamate receptor, ionotropic, kainate 1
  • domestic guinea pig(100735908) glutamate receptor, ionotropic, kainate 1
  • Domestic Rabbit(100354052) glutamate receptor, ionotropic, kainate 1
  • sheep(101107319) glutamate receptor, ionotropic, kainate 1

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Small Molecule - Agonist

Product Number
Description
Species
A263
ATPA, solid,
Species
human, rat
G2128
L-Glutamic acid hydrochloride, ≥99% (HPLC),
Species
human
Q2128
Quisqualic acid, powder,
Species
rat
M3262
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
Species
human, rat
A6816
(±)-AMPA, solid,
Species
rat

Small Molecule - Antagonist

Product Number
Description
Species
A5282
DL-2-Amino-5-phosphonopentanoic acid, solid,
Species
rat
144789
2,3-Dihydroxyquinoxaline, 98%,
Species
rat
A6553
DL-2-Amino-5-phosphonovaleric acid lithium salt, ~95%,
Species
rat
A263
ATPA, solid,
Species
human, rat
P7575
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
MAB379
Anti-Glutamate Receptor 5, 6, 7 Antibody, clone 4F5, ascites fluid, clone 4F5, Chemicon®,
Species Reactivity
human, monkey, rat
Application
ELISA
immunocytochemistry
immunohistochemistry
radioimmunoassay
07-258
Anti-GluR5 Antibody, Upstate®, from rabbit,
Species Reactivity
rat
Application
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
A263
ATPA, solid,
Species
human, rat
A6816
(±)-AMPA, solid,
Species
rat
K0250
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
G1251
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
G8415
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human