Merck
CN

GRIK3

glutamate receptor, ionotropic, kainate 3

Synonyms:
EAA5, GLR7, GLUR7, GluK3, GluR7a
Species:
UniProtKB ID:
Gene ID:
  • Human(2899) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008]
  • Mouse(14807) glutamate receptor, ionotropic, kainate 3
  • Rat(298521) glutamate receptor, ionotropic, kainate 3
  • dog(608269) glutamate receptor, ionotropic, kainate 3
  • sheep(101114065) glutamate receptor, ionotropic, kainate 3
  • chicken(419619) glutamate receptor, ionotropic, kainate 3
  • domestic cat(101090033) glutamate receptor, ionotropic, kainate 3
  • cow(532553) glutamate receptor, ionotropic, kainate 3

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Small Molecule - Agonist

Product Number
Description
Species
L-Glutamic acid hydrochloride, ≥99% (HPLC),
Species
human
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human

Small Molecule - Antagonist

Product Number
Description
Species
NBQX disodium salt hydrate, ≥98% (HPLC),
Species
human
DNQX, ≥98% (TLC),
Species
mouse, rat, human
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GRIK3 antibody produced in mouse, clone 4H1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-Grik3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-GRIK3/GLUR7 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, canine, human, mouse, rat
Application
ELISA
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Kainic acid monohydrate, ≥99% (TLC),
Species
human, mouse, rat
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Species
rat, human
L-Glutamic acid, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
Species
rat, human
L-Glutamic acid, BioUltra, ≥99.5% (NT),
Species
rat, human
L-Glutamic acid, FCC,
Species
rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GRIK3,
Species
human
MISSION® esiRNA, targeting mouse Grik3,
Species
mouse