CN
HRAS
Harvey rat sarcoma viral oncogene homolog
Synonyms:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
Species:
Human HRAS (3265), Rat Hras (293621), dog HRAS (403735), cow HRAS (100298939), naked mole-rat Hras (101716053), chicken HRAS (396229), domestic guinea pig Hras (100735038), sheep HRAS (101104357)
UniProtKB ID:
Gene ID:
- Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Rat(293621) Harvey rat sarcoma virus oncogene
- dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Custom & Knockdown Gene Products
siRNA
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shRNA
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Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Product Number
Description
Species
Guanosine 5′-triphosphate sodium salt solution, HPLC purified, aqueous solution for RNA polymerase transcription,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HRAS antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-HRAS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-H-Ras Antibody, clone 7D7.2, clone 7D7.2, Chemicon®, from mouse,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-RASH antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-HRAS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot
western blot
esiRNA
Product Number
Description
Species