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MYD88

myeloid differentiation primary response 88

Synonyms:
MYD88D
Species:
UniProtKB ID:
Gene ID:
  • Human(4615) Summary: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
  • Mouse(17874) myeloid differentiation primary response gene 88
  • Rat(301059) myeloid differentiation primary response 88
  • Zebrafish(403145) myeloid differentiation primary response gene (88)
  • fruit fly(35956) CG2078 gene product from transcript CG2078-RB
  • chicken(420420) myeloid differentiation primary response gene (88)
  • dog(477024) myeloid differentiation primary response gene (88)
  • naked mole-rat(101712637) myeloid differentiation primary response 88
  • cow(444881) myeloid differentiation primary response gene (88)
  • sheep(678682) myeloid differentiation primary response gene (88)
  • domestic guinea pig(100733381) myeloid differentiation primary response 88
  • domestic cat(101087092) myeloid differentiation primary response gene (88)

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MyD88 antibody produced in mouse, clone 2E9C2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
KD-Validated Anti MYD88 Antibody, clone 24GB240, Rabbit Monoclonal, clone 24GB240, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human
Application
flow cytometry
immunofluorescence

western blot
Anti-MyD88 Antibody, CT, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
western blot
Anti-MYD88, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-MYD88 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, chimpanzee, human, mouse, rat
Application
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Myd88,
Species
mouse
MISSION® esiRNA, targeting human MYD88,
Species
human