OSCAR
osteoclast associated, immunoglobulin-like receptor
Synonyms:
PIGR3, PIgR-3
Species:
Human OSCAR (126014), Mouse Oscar (232790), Rat Oscar (292537), cow OSCAR (100336423), dog OSCAR (484313)
UniProtKB ID:
Gene ID:
- Human(126014) Summary: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(232790) osteoclast associated receptor
- Rat(292537) osteoclast associated, immunoglobulin-like receptor
- cow(100336423) osteoclast associated, immunoglobulin-like receptor
- dog(484313) osteoclast associated, immunoglobulin-like receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-OSCAR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence