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SIRT2

sirtuin 2

Synonyms:
SIR2, SIR2L, SIR2L2
Species:
Human SIRT2 (22933), Mouse Sirt2 (64383), Rat Sirt2 (361532), dog SIRT2 (612558), chicken SIRT2 (548628), domestic guinea pig Sirt2 (100734519), cow SIRT2 (504463), Zebrafish sirt2 (322309), sheep SIRT2 (101113169), domestic cat SIRT2 (101099513) ...More
UniProtKB ID:
Q8IXJ6, A8K3V1, B2RB45, O95889, Q924Y7, Q9P0G8, Q9UNT0, Q9Y6E9
Gene ID:
  • Human(22933) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
  • Mouse(64383) sirtuin 2
  • Rat(361532) sirtuin 2
  • dog(612558) sirtuin 2
  • chicken(548628) sirtuin 2
  • domestic guinea pig(100734519) sirtuin 2
  • cow(504463) sirtuin 2
  • Zebrafish(322309) sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
  • sheep(101113169) sirtuin 2
  • domestic cat(101099513) sirtuin 2
  • fruit fly(42414) CG5085 gene product from transcript CG5085-RA
  • naked mole-rat(101715152) sirtuin 2

Custom & Knockdown Gene Products

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
RAB1700
Human Sirtuin 2 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
47865-U
Nicotinamide (Niacinamide), analytical standard,
Species
human
N5535
Niacinamide, meets USP testing specifications,
Species
human
N0636
Nicotinamide, BioReagent, suitable for cell culture, suitable for insect cell culture,
Species
human
N3376
Nicotinamide, ≥98% (HPLC), powder,
Species
human
72340
Nicotinamide, ≥99.5% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
HPA011165
Anti-SIRT2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
ChIP
immunofluorescence
immunohistochemistry
WH0022933M1
Monoclonal Anti-SIRT2 antibody produced in mouse, clone 4B11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
SAB5702385
Anti-SIRT2 Antibody, clone 1E1U3, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot
ZRB2596
Anti-SIRT2 Antibody, clone 1D4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunohistochemistry
western blot
09-843
Anti-SIRT2 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot

Proteins

Product Number
Description
Species
SRP0116
Sirtuin 2 human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EMU017211
MISSION® esiRNA, targeting mouse Sirt2,
Species
mouse