TTK
TTK protein kinase
Synonyms:
CT96, ESK, MPH1, MPS1, MPS1L1, PYT
Species:
Human TTK (7272), Mouse Ttk (22137), Rat Ttk (315852), Zebrafish ttk (317763), fruit fly ttk (48317), chicken TTK (421849), dog TTK (481895), Horse TTK (100069586), domestic cat TTK (101101566), sheep TTK (101113682) ...More
UniProtKB ID:
Gene ID:
- Human(7272) Summary: This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
- Mouse(22137) Ttk protein kinase
- Rat(315852) Ttk protein kinase
- Zebrafish(317763) ttk protein kinase
- fruit fly(48317) tramtrack
- chicken(421849) TTK protein kinase
- dog(481895) TTK protein kinase
- Horse(100069586) TTK protein kinase
- domestic cat(101101566) TTK protein kinase
- sheep(101113682) TTK protein kinase
- cow(524925) TTK protein kinase
- Domestic Rabbit(100359213) TTK protein kinase
- domestic guinea pig(100723582) TTK protein kinase
- naked mole-rat(101702153) TTK protein kinase
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TTK, (N-terminal) antibody produced in mouse, clone 4G9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot