106577
2-Iodohippuric acid
98%
Synonym(s):
N-(2-Iodobenzoyl)glycine
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About This Item
Linear Formula:
IC6H4CONHCH2CO2H
CAS Number:
Molecular Weight:
305.07
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-693-5
Beilstein/REAXYS Number:
1877943
MDL number:
InChI key
CORFWQGVBFFZHF-UHFFFAOYSA-N
InChI
1S/C9H8INO3/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)
SMILES string
OC(=O)CNC(=O)c1ccccc1I
assay
98%
reaction suitability
reaction type: solution phase peptide synthesis
mp
170-172 °C (lit.)
Quality Level
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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W M Michels et al.
Clinical nephrology, 72(5), 337-343 (2009-10-30)
Measuring GFR using exogenous markers without a bladder catheter, errors can be easily made due to incomplete urine collection. The aim was to quantify agreement for 125I-iothalamate GFR measurements with and without a correction for inaccurate urine collection using 131I-hippuran.
Andrew T Taylor et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(4), 578-584 (2013-02-21)
The pharmacokinetics of the tricarbonyl core radiopharmaceutical (99m)Tc(CO)3-nitrilotriacetic acid ((99m)Tc(CO)3(NTA)) in rats and subjects with normal renal function are comparable to those of (131)I-o-iodohippuran ((131)I-OIH), the radiopharmaceutical gold standard for the measurement of effective renal plasma flow. Our objective was
Andrew T Taylor et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 45(5), 885-891 (2004-05-12)
99mTc-Mercaptoacetyltriglycine ((99m)Tc-MAG3) and (99m)Tc-L,L-ethylenedicysteine ((99m)Tc-LL-EC) are useful renal radiopharmaceuticals; however, both agents have renal clearances less than that of (131)I-orthoiodohippurate ((131)I-OIH), and (99m)Tc-LL-EC exists in dianionic and monoanionic forms at physiologic pH. In an effort to develop a superior (99m)Tc
M Barceló-Oliver et al.
Journal of inorganic biochemistry, 101(4), 649-659 (2007-02-13)
The X-ray structure of the [Cu(I-hip)(phen)2](+).(I-hip-).(H2O)7 complex (1) (where I-hipH is referred to o-iodohippuric acid and phen is 1,10-phenanthroline) and its binary synthetic intermediate [Cu(I-hip)2(H2O)3].(H2O)2 (2) have been solved and characterized by different techniques. This ternary [Cu(I-hip)(phen)2]+.(I-hip-).7H2O complex generates the
Gopal Pathuri et al.
Nuclear medicine communications, 32(10), 908-912 (2011-08-31)
We recently identified p-[(18)F]fluorohippurate ([(18)F]PFH) as a potential positron emission tomography (PET) renal agent. The objective of this study was to compare renogram parameters of [(18)F]PFH with o-[(125)I]iodohippurate ([(125)I]OIH) as a surrogate for the renal imaging gold standard (131)I-OIH and
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