14580
Nα,Nα-Bis(carboxymethyl)-L-lysine hydrate
≥97.0% (TLC), for peptide synthesis
Synonym(s):
(S)-N-(5-Amino-1-carboxypentyl)iminodiacetic acid
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About This Item
Empirical Formula (Hill Notation):
C10H18N2O6 · xH2O
CAS Number:
Molecular Weight:
262.26 (anhydrous basis)
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22
Beilstein/REAXYS Number:
9141770
MDL number:
Product Name
Nα,Nα-Bis(carboxymethyl)-L-lysine hydrate, ≥97.0% (TLC)
Quality Level
assay
≥97.0% (TLC)
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
application(s)
peptide synthesis
SMILES string
O.NCCCC[C@H](N(CC(O)=O)CC(O)=O)C(O)=O
InChI
1S/C10H18N2O6.H2O/c11-4-2-1-3-7(10(17)18)12(5-8(13)14)6-9(15)16;/h7H,1-6,11H2,(H,13,14)(H,15,16)(H,17,18);1H2/t7-;/m0./s1
InChI key
WTVPNZLAZFGAFK-FJXQXJEOSA-N
General description
Nα,Nα-Bis(carboxymethyl)-L-lysine hydrate is a synthetic amino acid used in solution phase peptide synthesis.
Application
<ul>
<li><strong>N and alpha;N and alpha;-Bis(carboxymethyl)-lysine hydrate in Biosensor Development:</strong> Zhang et al. explored the use of functionalized graphene oxide for the fabrication of biosensors aimed at detecting paraoxon, a nerve agent, where N and alpha;N and alpha;-Bis(carboxymethyl)-lysine hydrate is used as a part of the step-by-step process to anchor onto the GO-based materials (Zhang et al., 2014).</li>
<li><strong>Protein Purification Enhancements:</strong>N,N-Bis(carboxymethyl)-l-lysine hydrate (ANTA) is used in the synthesis of superparamagnetic Fe3O4/Au nanoparticles as a conjugating agent. It facilitates the attachment of Co2+ ions to the surface-modified Fe3O4/Au nanoparticles, resulting in the formation of Fe3O4/Aun and ndash;ANTA and ndash;Co2+ nanoparticles (Zhang et al., 2013).</li>
</ul>
<li><strong>N and alpha;N and alpha;-Bis(carboxymethyl)-lysine hydrate in Biosensor Development:</strong> Zhang et al. explored the use of functionalized graphene oxide for the fabrication of biosensors aimed at detecting paraoxon, a nerve agent, where N and alpha;N and alpha;-Bis(carboxymethyl)-lysine hydrate is used as a part of the step-by-step process to anchor onto the GO-based materials (Zhang et al., 2014).</li>
<li><strong>Protein Purification Enhancements:</strong>N,N-Bis(carboxymethyl)-l-lysine hydrate (ANTA) is used in the synthesis of superparamagnetic Fe3O4/Au nanoparticles as a conjugating agent. It facilitates the attachment of Co2+ ions to the surface-modified Fe3O4/Au nanoparticles, resulting in the formation of Fe3O4/Aun and ndash;ANTA and ndash;Co2+ nanoparticles (Zhang et al., 2013).</li>
</ul>
Analysis Note
may contain up ~2 mol water and ~10% inorganic salts
Other Notes
Tricarboxylic acid used for preparing chelating resins employed for the chromatography of proteins
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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E Hochuli et al.
Journal of chromatography, 411, 177-184 (1987-12-18)
A novel nitrilotriacetic acid adsorbent has been prepared for metal chelate affinity chromatography. The new resin is a quadridentate chelate former and specially suitable for metal ions with coordination numbers of six, since two valencies remain for the reversible binding
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 14580-5G | 04061838736451 |
| 14580-1G | 04061838736444 |