165344
1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide
for peptide synthesis
Synonym(s):
EDC methiodide
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About This Item
Linear Formula:
C2H5N=C=N(CH2)3N(CH3)3I
CAS Number:
Molecular Weight:
297.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
245-095-1
MDL number:
Product Name
1-[3-(Dimethylamino)propyl]-3-ethylcarbodiimide methiodide,
form
powder
Quality Level
reaction suitability
reaction type: Coupling Reactions
mp
97-99 °C (lit.)
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
SMILES string
[I-].CCN=C=NCCC[N+](C)(C)C
InChI
1S/C9H20N3.HI/c1-5-10-9-11-7-6-8-12(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChI key
AGSKWMRPXWHSPF-UHFFFAOYSA-M
Application
- Crosslinking agent
Reactant for:
- Amide bond forming (amidation) crosslinking reactions
Water-soluble carboxyl modifying reagent for proteins.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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A K Tsaturyan et al.
Biophysical journal, 77(1), 354-372 (1999-07-02)
Structural changes induced by Joule temperature jumps (T-jumps) in frog muscle fibers were monitored using time-resolved x-ray diffraction. Experiments made use of single, permeabilized fibers that were fully activated after slight cross-linking with 1-ethyl-3-[3-dimethylamino)propyl]carbodiimide to preserve their structural order. After
Heather M Powell et al.
Biomaterials, 28(6), 1084-1092 (2006-11-07)
Collagen-glycosaminoglycan (C-GAG) sponges are commonly utilized as a substitute for the extracellular matrix of dermal tissue. Cultured skin substitutes (CSS) were assessed, after fabrication using sponges cross-linked with 1-ethyl-3-3-dimethylaminopropylcarbodiimide hydrochloride (EDC) at 0, 1, 5, or 50 mm, for development
Takahiro Kishimoto et al.
Biopolymers, 79(3), 163-172 (2005-08-12)
Pro-Hyp-Gly is a characteristic amino acid sequence found in fibrous collagens, and (Pro-Hyp-Gly)(10), which has been widely used as a collagen-model peptide, forms a stable triple-helical structure. Here, we synthesized polypeptides consisting of the Pro-Hyp-Gly sequence by direct poly-condensation of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 165344-10G | 04061838748669 |
| 165344-1G | 04061838748676 |