Skip to Content
Merck
CN

17308

N,N-Dimethylacetamide

suitable for peptide synthesis, ≥99.8% (GC)

Synonym(s):

DMA, DMAc, Dimethylacetamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
CH3CON(CH3)2
CAS Number:
127-19-5
Molecular Weight:
87.12
UNSPSC Code:
12352111
NACRES:
NA.22
PubChem Substance ID:
57647631
EC Number:
204-826-4
Beilstein/REAXYS Number:
1737614
MDL number:
MFCD00008686
Assay:
≥99.8% (GC)
Technique(s):
GC/GC: suitable
Application(s):
peptide synthesis
Bp:
164.5-166 °C (lit.)
Vapor pressure:
2 mmHg ( 25 °C)
4 mmHg ( 38 °C)

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

N,N-Dimethylacetamide, suitable for peptide synthesis, ≥99.8% (GC)

InChI key

FXHOOIRPVKKKFG-UHFFFAOYSA-N

InChI

1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

SMILES string

CN(C)C(C)=O

vapor density

3 (vs air)

vapor pressure

2 mmHg ( 25 °C)
4 mmHg ( 38 °C)

assay

≥99.8% (GC)

form

liquid

autoignition temp.

914 °F

expl. lim.

1.8 %, 100 °F
11.5 %, 160 °F

technique(s)

GC/GC: suitable

impurities

≤0.02% water

refractive index

n20/D 1.437 (lit.)
n20/D 1.438

pH

4 (20 °C, 200 g/L)

bp

164.5-166 °C (lit.)

mp

−20 °C (lit.)

density

0.937 g/mL at 25 °C (lit.)

suitability

in accordance for amine test

application(s)

peptide synthesis

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

N,N-Dimethylacetamide (DMA) can be used as a solvent in peptide synthesis.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN7872
BCCN2729
BCCM0877
BCCM5018
BCCL5245

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Total synthesis of the thiazolyl peptide GE2270 A
Muller HM, et al.
Angewandte Chemie (International Edition in English), 46(25), 4771-4774 (2007)
The Horner-Wadsworth-Emmons reaction in the synthesis of macrocyclic peptides: the Trp-His-Gly-Arg derived macrocycle of moroidin
Harrison JR and Moody CJ
Tetrahedron Letters, 44(28), 5189-5191 (2003)
Peptides derived from nucleoside β-amino acids form an unusual 8-helix
Threlfall R, et al.
Chemical Communications (Cambridge, England), 46(5), 585-587 (2008)
Inês Farinha et al.
Carbohydrate polymers, 130, 455-464 (2015-06-17)
Purified chitin-glucan complex (CGCpure) was extracted from Komagataella pastoris biomass using a hot alkaline treatment, followed by neutralization and repeated washing with deionized water. The co-polymer thus obtained had a β-glucan:chitin molar ratio of 75:25 and low protein and inorganic
André H Gröschel et al.
Nature communications, 3, 710-710 (2012-03-20)
Hierarchical self-assembly offers elegant and energy-efficient bottom-up strategies for the structuring of complex materials. For block copolymers, the last decade witnessed great progress in diversifying the structural complexity of solution-based assemblies into multicompartment micelles. However, a general understanding of what
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service