233412
Ethyl (hydroxyimino)cyanoacetate
97%, for peptide synthesis
Synonym(s):
Ethyl cyano(hydroxyimino)acetate, Ethyl cyanoglyoxalate-2-oxime, Ethyl isonitrosocyanoacetate
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About This Item
Linear Formula:
NCC(=NOH)CO2C2H5
CAS Number:
Molecular Weight:
142.11
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
223-351-3
MDL number:
Beilstein/REAXYS Number:
774783
Product Name
Ethyl (hydroxyimino)cyanoacetate, 97%
Quality Level
assay
97%
form
solid
mp
130-132 °C (lit.)
application(s)
peptide synthesis
functional group
amine, ester, nitrile, oxime
SMILES string
CCOC(=O)C(=N\O)\C#N
InChI
1S/C5H6N2O3/c1-2-10-5(8)4(3-6)7-9/h9H,2H2,1H3/b7-4+
InChI key
LCFXLZAXGXOXAP-QPJJXVBHSA-N
General description
Ethyl (hydroxyimino)cyanoacetate is a potential replacement for zobenzotriazole and benzotriazole derivatives used in peptide synthesis.
Ethyl (hydroxyimino)cyanoacetate is also called as Oxyma. It is a highly efficient greener alternative for the amide and peptide synthesis.
Ethyl (hydroxyimino)cyanoacetate is also called as Oxyma. It is a highly efficient greener alternative for the amide and peptide synthesis.
Application
Ethyl (hydroxyimino)cyanoacetate has been used as an additive for the carbodiimide-mediated amide bond formation during established peptide synthesis method.For peptide synthesis grade material, please see product 851086.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Alvin W Hung et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(17), 6799-6804 (2011-04-13)
Fragment-based drug discovery (FBDD) has proven to be an effective means of producing high-quality chemical ligands as starting points for drug-discovery pursuits. The increasing number of clinical candidate drugs developed using FBDD approaches is a testament of the efficacy of
Miriam Reverter et al.
Metabolites, 10(6) (2020-06-04)
Understanding natural defense mechanisms against parasites can be a valuable tool for the development of innovative therapies. We have previously identified a butterflyfish species (Chaetodonlunulatus) that avoids gill monogenean parasites while living amongst closely related parasitized species. The metabolome and
Hangyu Zhang et al.
Acta biomaterialia, 55, 183-193 (2017-04-04)
Self-assembling peptides programed by sequence design to form predefined nanostructures are useful for a variety of biomedical applications. However, assemblies of classic ionic self-complementary peptides are unstable in neutral pH, while charged peptide hydrogels have low mechanical strength. Here, we
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 233412-50G | 04061838784025 |
| 233412-250G | 04061838784018 |