260789
8-Aminoquinoline
98%
Synonym(s):
8-Quinolinamine
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About This Item
Empirical Formula (Hill Notation):
C9H8N2
CAS Number:
Molecular Weight:
144.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-427-9
Beilstein/REAXYS Number:
114474
MDL number:
Assay:
98%
Form:
solid
InChI key
WREVVZMUNPAPOV-UHFFFAOYSA-N
InChI
1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2
SMILES string
Nc1cccc2cccnc12
assay
98%
form
solid
reaction suitability
reaction type: C-H Activation, reagent type: catalyst
bp
174 °C/26 mmHg (lit.)
Quality Level
mp
60-65 °C (lit.)
Related Categories
General description
8-Aminoquinoline fluoresce moderately to weakly in low dielectric media but not in strongly hydrogen-bonding or acidic aqueous media. The reaction of 8-aminoquinoline with chromium (III), manganese (II), iron (II) and (III), cobalt (II), nickel (II), copper (II), zinc (II), cadmium (II) and platinum (II) salts has been studied.
Application
8-Aminoquinoline has been used in:
- preparation of base-stabilized terminal borylene complex of osmium
- spectrophotometric determination of bivalent palladium
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Shyamaprosad Goswami et al.
Chemical communications (Cambridge, England), 47(32), 9101-9103 (2011-07-07)
A new fluorescence rhodamine derivative bearing an 8-aminoquinoline moiety has been designed and synthesized for selective sensing of Pd(2+) in the presence of other competing metal ions in aqueous media. Pd(2+) induced spirolactam ring opening of rhodamine is confirmed for
Lorenz von Seidlein et al.
Malaria journal, 12, 112-112 (2013-03-30)
The diagnosis and management of glucose-6-phosphate dehydrogenase (G6PD) deficiency is a crucial aspect in the current phases of malaria control and elimination, which will require the wider use of 8-aminoquinolines for both reducing Plasmodium falciparum transmission and achieving the radical
Paul Abu-Rabie et al.
Analytical chemistry, 83(22), 8779-8786 (2011-10-07)
A novel technique is presented that addresses the issue of how to apply internal standard (IS) to dried matrix spot (DMS) samples that allows the IS to integrate with the sample prior to extraction. The TouchSpray, a piezo electric spray
A Base-Stabilized Terminal Borylene Complex of Osmium Derived from Reaction between a Dichloroboryl Complex and 8-Aminoquinoline This work was supported by the Marsden Fund administered by The Royal Society of New Zealand.
Irvine et al.
Angewandte Chemie (International ed. in English), 39(5), 948-950 (2000-04-13)
Liangliang Yan et al.
Journal of inorganic biochemistry, 106(1), 46-51 (2011-11-25)
Palladium(II) complexes are potential antitumor metallodrugs for their chemical resemblance to platinum(II) complexes. Two palladium(II) complexes (1 and 2) in the formula of [PdL(n)Cl] [L(1) = N-(tert-butoxycarbonyl)-l-methionine-N'-8-quinolylamide, L(2) = L-alanine-N'-8-quinolylamide] have been synthesized accordingly. The structures of the complexes were
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