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Merck
CN

279315

Sodium acetate-2-13C

99 atom % 13C

Synonym(s):

Acetic-2-13C acid sodium salt

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About This Item

Linear Formula:
13CH3CO2Na
CAS Number:
Molecular Weight:
83.03
UNSPSC Code:
12142200
NACRES:
NA.12
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4211334
Isotopic purity:
99 atom % 13C
Mass shift:
M+1
Form:
solid
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isotopic purity

99 atom % 13C

Quality Segment

form

solid

technique(s)

bio NMR: suitable, protein expression: suitable

mp

>300 °C (dec.) (lit.)

mass shift

M+1

SMILES string

[Na+].[13CH3]C([O-])=O

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1/i1+1;

InChI key

VMHLLURERBWHNL-YTBWXGASSA-M

General description

Sodium acetate-2-13C is 13C isotopomer labeled precursor of sodium acetate.

Application

13C labeling in the methyl group has a significant effect on the Dynamic Nuclear Polarization of acetate. Sodium acetate-2-13C labeling can be used in structural studies analyzing the interactions between lipo oligosaccharide and host proteins. Incorporation of Sodium acetate-2-13C shows enriched 13C-NMR spectra indicating their biosynthesis of microbial products and novel polyketides. Hyperpolarized 13C-acetate MRI has been applied to examinations of both rodents and porcine models.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Peter Niedbalski et al.
The journal of physical chemistry. A, 121(17), 3227-3233 (2017-04-20)
Dynamic nuclear polarization (DNP) via the dissolution method has alleviated the insensitivity problem in liquid-state nuclear magnetic resonance (NMR) spectroscopy by amplifying the signals by several thousand-fold. This NMR signal amplification process emanates from the microwave-mediated transfer of high electron
Deborah M B Post et al.
Journal of endotoxin research, 12(2), 93-98 (2006-05-13)
The lipooligosaccharide (LOS) of a Neisseria meningitidis acetate auxotroph was metabolically labeled with either [2-13C]-sodium acetate or [1,2-13C2]-sodium acetate. In this study, we demonstrated that this label was efficiently incorporated into both the lipid A acyl moieties and the two
Emmeli F R Mikkelsen et al.
Scientific reports, 7(1), 16002-16002 (2017-11-24)
11C-acetate is a positron emission tomography (PET) tracer of oxidative metabolism, whereas hyperpolarized 13C-acetate can be used in magnetic resonance imaging (MRI) for investigating specific metabolic processes. The aims of this study were to examine if the kinetic formalism of



Global Trade Item Number

SKUGTIN
279315-1G04061826671412