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292915

2-Pyrrolidone-5-carboxylic acid

Name: 2-Pyrrolidone-5-carboxylic acid
Brand: ALDRICH

99%

Synonym(s):

DL-5-Oxo-2-pyrrolidinecarboxylic acid, DL-Pyroglutamic acid

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About This Item

Empirical Formula (Hill Notation):

C₅H₇NO₃

CAS Number:

149-87-1

Molecular Weight:

129.11

UNSPSC Code:

12352106

NACRES:

NA.22

PubChem Substance ID:

24857617

EC Number:

205-748-3

Beilstein/REAXYS Number:

82134

MDL number:

MFCD00064322

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Properties

Quality Level

200

assay

99%

reaction suitability

reaction type: solution phase peptide synthesis

mp

183-185 °C (lit.)

application(s)

peptide synthesis

SMILES string

OC(=O)C1CCC(=O)N1

InChI

1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)

InChI key

ODHCTXKNWHHXJC-UHFFFAOYSA-N

Description

General description

DL-Pyroglutamic acid serves as a chiral building block and a chiral auxiliary in asymmetric synthesis.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Pyroglutamic acid: a versatile building block in asymmetric synthesis

C Najera, et al.

Tetrahedron Asymmetry, 10, 2245-2303 (1999)

A Novel Composite Hydrogel Composed of Formic Acid-Decellularized Pepsin-Soluble Extracellular Matrix Hydrogel and Sacchachitin Hydrogel as Wound Dressing to Synergistically Accelerate Diabetic Wound Healing.

Chien-Ming Hsieh et al.

Pharmaceutics, 12(6) (2020-06-18)

Extracellular matrix (ECM) hydrogel can create a favorable regenerative microenvironment and act as a promising dressing for accelerating the healing of diabetic wound. In this study, a simple and effective decellularization technique was developed and optimized to obtain acellular extracellular

Translating chemometric analysis into physiological insights from in vivo confocal Raman spectroscopy of the human stratum corneum.

Stefania Perticaroli et al.

Biochimica et biophysica acta. Biomembranes, 1861(2), 403-409 (2018-11-23)

The superficial layer of the skin, the stratum corneum (SC), consists of corneocytes surrounded by lipid regions and acts as a protective barrier for the body against water loss, toxic agents and microorganisms. As most substances permeate the stratum corneum

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Global Trade Item Number

SKU	GTIN
292915-5G	04061826595169
292915-100G	04061826595152