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Merck
CN

302430

Methylmagnesium bromide solution

1.0 M in dibutyl ether

Synonym(s):

Bromomethylmagnesium

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About This Item

Linear Formula:
CH3MgBr
CAS Number:
75-16-1
Molecular Weight:
119.24
UNSPSC Code:
12352111
NACRES:
NA.22
PubChem Substance ID:
24858252
MDL number:
MFCD00000041
Beilstein/REAXYS Number:
3535220

Key Documents

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Product Name

Methylmagnesium bromide solution, 1.0 M in dibutyl ether

InChI

1S/CH3.BrH.Mg/h1H3;1H;/q;;+1/p-1

SMILES string

C[Mg]Br

InChI key

AVFUHBJCUUTGCD-UHFFFAOYSA-M

reaction suitability

reaction type: Grignard Reaction

concentration

1.0 M in dibutyl ether

density

0.856 g/mL at 25 °C

Quality Level

100

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Related Categories

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3 - Water-react 1

target_organs

Respiratory system

Storage Class

4.3 - Hazardous materials which set free flammable gases upon contact with water

wgk

WGK 1

flash_point_f

82.4 °F - closed cup

flash_point_c

28 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
SHBL8923
SHBG7131V
SHBF6966V
SHBB7316V
53496MM

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Snahel Patel et al.
Journal of medicinal chemistry, 58(1), 401-418 (2014-10-24)
Dual leucine zipper kinase (DLK, MAP3K12) was recently identified as an essential regulator of neuronal degeneration in multiple contexts. Here we describe the generation of potent and selective DLK inhibitors starting from a high-throughput screening hit. Using proposed hinge-binding interactions

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