330639
L-Alanine methyl ester hydrochloride
99%, for peptide synthesis
Synonym(s):
(S)-2-Aminopropionic acid methyl ester hydrochloride, L-Ala-OMe·HCl
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About This Item
Linear Formula:
CH3CH(NH2)COOCH3 · HCl
CAS Number:
Molecular Weight:
139.58
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
219-652-4
MDL number:
Beilstein/REAXYS Number:
3594033
Product Name
L-Alanine methyl ester hydrochloride, 99%
Quality Level
assay
99%
optical activity
[α]25/D +7.0°, c = 1.6 in methanol
reaction suitability
reaction type: solution phase peptide synthesis
mp
109-111 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl.COC(=O)[C@H](C)N
InChI
1S/C4H9NO2.ClH/c1-3(5)4(6)7-2;/h3H,5H2,1-2H3;1H/t3-;/m0./s1
InChI key
IYUKFAFDFHZKPI-DFWYDOINSA-N
General description
L-Alanine methyl ester hydrochloride also known as L-Ala-OMe·HCl, is a versatile reagent used commonly in solution phase peptide synthesis. It is often used to synthesize dipeptides.
Application
L-Alanine methyl ester hydrochloride can be used as a starting material in the synthesis of alanine isoxazolidide via solution phase peptide synthesis. Additionally, it is used to synthesize N-Fmoc-l-alanyl-l-alanine methyl ester and α-amino acid-based sector block dendrons.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The dimethylsulfoxonium methylide as unique reagent for the simultaneous deprotection of amino and carboxyl function of N-Fmoc-?-amino acid and N-Fmoc-peptide esters
M Spinella
Tetrahedron, 69, 2010-2016 (2013)
Synthesis and gelation properties of a new class of $\alpha$-amino acid-based sector block dendrons
HF Chow
Tetrahedron, 61, 11279-11290 (2005)
Hala Bakr El-Nassan et al.
Pharmaceutical research, 35(8), 149-149 (2018-05-31)
To assess the gelation power of N-palmitoyl L-alanine derivatives in injectable oils and to use the best chosen organogel as parenteral implant of granisetron for the treatment of emesis. Twelve N-palmitoyl L-alanine derived organogels were developed and evaluated in terms
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 330639-25G | 04061826726105 |
| 330639-5G | 04061826726112 |
| 330639-100G | 04061832641959 |