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469971

L-Tryptophanol

Name: <SC>L</SC>-Tryptophanol
Brand: ALDRICH

97%

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₄N₂O

CAS Number:

2899-29-8

Molecular Weight:

190.24

NACRES:

NA.22

PubChem Substance ID:

24870628

UNSPSC Code:

12352209

MDL number:

MFCD00037970

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Properties

Quality Level

100

assay

97%

optical activity

[α]20/D −20.5°, c = 1 in methanol

reaction suitability

reaction type: solution phase peptide synthesis

mp

73-77 °C (lit.)

application(s)

peptide synthesis

SMILES string

N[C@H](CO)Cc1c[nH]c2ccccc12

InChI

1S/C11H14N2O/c12-9(7-14)5-8-6-13-11-4-2-1-3-10(8)11/h1-4,6,9,13-14H,5,7,12H2/t9-/m0/s1

InChI key

UDQCRUSSQAXPJY-VIFPVBQESA-N

Description

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Tryptophanyl-tRNA synthetase in cell lines resistant to tryptophan analogs.

E L Paley et al.

Experimental cell research, 195(1), 66-78 (1991-07-01)

Bovine kidney cell lines resistant to tryptamine and tryptophanol (tryptophan analogs) were selected. The content of tryptophanyl-tRNA synthetase (WRS, EC 6.1.1.2) was assayed by measuring the binding of monospecific polyclonal antibodies to the 35S-labeled enzyme in detergent-soluble and -insoluble forms

Quantifying prefibrillar amyloids in vitro by using a "thioflavin-like" spectroscopic method.

Ashley A Reinke et al.

Chembiochem : a European journal of chemical biology, 11(13), 1889-1895 (2010-08-03)

In Alzheimer's disease (AD) and other neurodegenerative disorders, proteins accumulate into ordered aggregates, called amyloids. Recent evidence suggests that these structures include both large, insoluble fibrils and smaller, prefibrillar structures, such as dimers, oligomers, and protofibrils. Recently, focus has shifted

Activation of General Control Nonderepressible-2 Kinase Ameliorates Glucotoxicity in Human Peritoneal Mesothelial Cells, Preserves Their Integrity, and Prevents Mesothelial to Mesenchymal Transition.

Theodoros Eleftheriadis et al.

Biomolecules, 9(12) (2019-12-11)

Along with infections, ultrafiltration failure due to the toxicity of glucose-containing peritoneal dialysis (PD) solutions is the Achilles' heel of PD method. Triggered by the protective effect of general control nonderepressible-2 (GCN-2) kinase activation against high-glucose conditions in other cell

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Global Trade Item Number

SKU	GTIN
469971-1G	04061826222324