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47517

Fmoc-Hyp(tBu)-OH

≥98.0% (HPLC)

Synonym(s):

Fmoc-O-tert-butyl-L-hydroxyproline

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About This Item

Empirical Formula (Hill Notation):
C24H27NO5
CAS Number:
122996-47-8
Molecular Weight:
409.47
NACRES:
NA.26
PubChem Substance ID:
57650984
eCl@ss:
32160406
UNSPSC Code:
12352209
MDL number:
MFCD00151930
Beilstein/REAXYS Number:
6161467
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Quality Level

100

assay

≥98.0% (HPLC)

optical activity

[α]20/D −25±2.5°, c = 1% in methanol

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

CC(C)(C)O[C@@H]1C[C@H](N(C1)C(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O

InChI

1S/C24H27NO5/c1-24(2,3)30-15-12-21(22(26)27)25(13-15)23(28)29-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,27)/t15-,21+/m1/s1

InChI key

WPBXBYOKQUEIDW-VFNWGFHPSA-N

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2642
BCCG2097
BCCC1284
BCBF2491V
BCBS5854V

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Articles

Proline Derivatives and Analogs

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

Julien Echterbille et al.
Toxicon : official journal of the International Society on Toxinology, 130, 1-10 (2017-02-28)
Animal toxins are peptides that often bind with remarkable affinity and selectivity to membrane receptors such as nicotinic acetylcholine receptors (nAChRs). The latter are, for example, targeted by α-conotoxins, a family of peptide toxins produced by venomous cone snails. nAChRs
Eugene Rogozhin et al.
International journal of molecular sciences, 19(11) (2018-11-08)
Herein, we describe a modified form of the antimicrobial hairpin-like peptide EcAMP1, isolated from barnyard grass (E. crusgalli) seeds, which is structurally characterized by a combination of high-pressure liquid chromatography, mass spectrometry, and automated Edman sequencing. This derivate has a
Lucas L Bennink et al.
Biomaterials, 183, 67-76 (2018-08-28)
Degradation of the extracellular matrix (ECM) is one of the fundamental factors contributing to a variety of life-threatening or disabling pathological conditions. However, a thorough understanding of the degradation mechanism and development of new ECM-targeting diagnostics are severely hindered by
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Global Trade Item Number

SKUGTIN
47517-5G-F04061832594798