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47623

Fmoc-Tyr(tBu)-OH

Name: Fmoc-Tyr(<I>t</I>Bu)-OH
Brand: ALDRICH

≥98.0% (HPLC), for peptide synthesis

Synonym(s):

N-(9-Fluorenylmethoxycarbonyl)-O-tert-butyl-L-tyrosine, Fmoc-O-tert-butyl-L-tyrosine

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About This Item

Empirical Formula (Hill Notation):

C₂₈H₂₉NO₅

CAS Number:

71989-38-3

Molecular Weight:

459.53

NACRES:

NA.26

PubChem Substance ID:

57651043

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

276-262-7

MDL number:

MFCD00037129

Beilstein/REAXYS Number:

4216652

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Properties

Product Name

Fmoc-Tyr(tBu)-OH, ≥98.0% (HPLC)

Quality Segment

100

assay

≥98.0% (HPLC)

form

powder

optical activity

[α]20/D −29±2°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

153-156 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

CC(C)(C)Oc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c4ccccc24)C(O)=O)cc1

InChI

1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m0/s1

InChI key

JAUKCFULLJFBFN-VWLOTQADSA-N

Description

General description

Fmoc-Tyr(tBu)-OH also known as Fmoc-O-tert-butyl-L-tyrosine, is commonly used in Fmoc solid phase peptide synthesis.

Application

Fmoc-Tyr(tBu)-OH can be used to synthesize Leu-EnkephalinAmide via solid phase synthesis in water. Additionally, it can be used to synthesize amino acid derivatives such as Fmoc-Tyr-OAllyl.

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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