47627
Fmoc-Gly-OH
≥98.0% (T)
Synonym(s):
Fmoc-glycine
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About This Item
Empirical Formula (Hill Notation):
C17H15NO4
CAS Number:
Molecular Weight:
297.31
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
249-373-3
MDL number:
Beilstein/REAXYS Number:
2163967
Quality Level
assay
≥98.0% (T)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
mp
174-175 °C (lit.), 174-178 °C
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
SMILES string
OC(=O)CNC(=O)OCC1c2ccccc2-c3ccccc13
InChI
1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20)
InChI key
NDKDFTQNXLHCGO-UHFFFAOYSA-N
Application
- Efficient Fmoc-Protected Amino Ester Hydrolysis Using Green Calcium (II) Iodide as a Protective Agent: This study describes the utilization of environmentally friendly calcium iodide in the hydrolysis of Fmoc-protected amino esters, enhancing reaction efficiency and sustainability (R Binette, M Desgagné, C Theaud, PL Boudreault - Molecules, 2022). Link to the article.
- α/β-Chimera peptide synthesis with cyclic β-sugar amino acids: the efficient coupling protocol: This research provides an advanced synthesis method for α/β-chimera peptides using cyclic β-sugar amino acids, demonstrating significant implications for peptide design in medicinal chemistry (A Nagy, V Goldschmidt Gőz, I Pintér, V Farkas - Amino acids, 2019). Link to the article.
- MS, CD, and FT-IR characterization of five newly synthesized histidine-containing Ala-and Gly-based peptides: This paper presents detailed characterization of novel histidine-containing peptides, highlighting techniques that could be pivotal for peptide-based drug discovery (M Murariu, L Ion, CI Ciobanu, BA Petre - Rev. Roum Chem., 2017). Link to the article.
- Efficient method for the concentration determination of fmoc groups incorporated in the core-shell materials by Fmoc–glycine: This article elaborates on an efficient method for determining the concentration of fmoc groups in core-shell materials, critical for the design of advanced functional materials (E Szczepańska, B Grobelna, J Ryl, A Kulpa - Molecules, 2020). Link to the article.
- Circular aqueous fmoc/t‐bu solid‐phase peptide synthesis: This study explores a novel approach in solid-phase peptide synthesis, utilizing circular aqueous techniques that may offer greener and more efficient methodologies for peptide synthesis (J Pawlas, JH Rasmussen - ChemSusChem, 2021). Link to the article.
Other Notes
Fmoc-glycine coupling of saccharide β-glycosylamines for the fractionation of oligosaccharides and formation of neoglycoconjugates.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Jing Fu et al.
Journal of hazardous materials, 368, 186-196 (2019-01-25)
Methyl-triclosan (MTCS), as a biodegradation product from antibacterial triclosan (TCS), has been detected in water catchments, and it has also been verified to accumulate in biota due to its hydrophobicity. There is a lack, however, of toxicity studies on MTCS
Jing Fu et al.
Ecotoxicology and environmental safety, 189, 110039-110039 (2019-12-13)
The omnipresence of antimicrobial triclosan (TCS) and by-products in aquatic environments is a threat to aquatic organisms. Traditionally, the adverse effects of TCS and its by-products have been evaluated by examining the phenotypic output relevant to predicting acute toxicity rather
L Noronha-Blob et al.
Gastroenterology, 104(4), 1021-1029 (1993-04-01)
The efficacy of the leukocyte recruitment inhibitor, N-[9H-2,7-dimethylfluoren-9-ylmethoxy)carbonyl]-L-leucine (NPC 15669) was compared with drugs used to treat inflammatory bowel diseases in a rat model, acetic acid-induced colitis. Colonic damage assessed by visual inspection, histological quantitation of tissue injury, vascular permeability
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 47627-5G-F | 04061832362311 |
| 47627-1KG-F | 04061826222720 |
| 47627-250G-F | 04061832362298 |
| 47627-50G-F | 04061832362304 |