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569755

Hoveyda-Grubbs Catalyst® M720

97%, Umicore, solid

greener alternative

Greener Alternative

Synonym(s):

Hoveyda-Grubbs Catalyst® 2nd Generation, Hoveyda-Grubbs Catalyst® M72 (C627), (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium, Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](2-isopropoxyphenylmethylene)ruthenium(II), Grubbs Catalyst® C627

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About This Item

Empirical Formula (Hill Notation):
C31H38Cl2N2ORu
CAS Number:
301224-40-8
Molecular Weight:
626.62
UNSPSC Code:
12161600
PubChem Substance ID:
24880520
NACRES:
NA.22
MDL number:
MFCD03701614
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Product Name

Hoveyda-Grubbs Catalyst® M720, Umicore, 97%

Quality Segment

product line

Grubbs Catalyst® M700 Series

assay

97%

form

solid

reaction suitability

reaction type: Olefin Metathesis, reagent type: catalyst
reaction type: Ring-Opening Polymerization, core: ruthenium

manufacturer/tradename

Umicore Grubbs Catalyst® M700 Series

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

216-220 °C (lit.)

greener alternative category

storage temp.

2-8°C

SMILES string

CC(C)Oc1ccccc1C=[Ru](Cl)(Cl)=C2N(CCN2c3c(C)cc(C)cc3C)c4c(C)cc(C)cc4C

InChI

1S/C21H26N2.C10H12O.2ClH.Ru/c1-14-9-16(3)20(17(4)10-14)22-7-8-23(13-22)21-18(5)11-15(2)12-19(21)6;1-8(2)11-10-7-5-4-6-9(10)3;;;/h9-12H,7-8H2,1-6H3;3-8H,1-2H3;2*1H;/q;;;;+2/p-2

InChI key

ZRPFJAPZDXQHSM-UHFFFAOYSA-L

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. This ruthenium catalyst exhibits high stability and recyclability for olefin metathesis reactions. Its remarkable tolerance to air, moisture, and diverse functional groups makes it invaluable for sustainable pharmaceutical and materials synthesis. Click here for more information.

Application

It′s a phosphine free version of Grubbs 2nd Generation Catalyst with comparable reactivity, but initiates more readily at lower temperatures. Efficient for metathesis of electron-deficient substrates including fluorinated olefins. Demonstrated in multiple large-scale pharmaceutical applications.
It can be used as a catalyst for olefin cross-metathesis with fluorinated olefins (CM), ring-closing metathesis (RCM), ring-opening metathesis (ROM), and a sequence of a metathesis reaction and subsequent dihydroxylation of the newly formed double bond.

Learn more about our metathesis catalysts

Other Notes

Grubbs Catalyst® Technology for Olefin Metathesis by Aldrich

Legal Information

Product of Umicore

Product License
This product, its manufacturing or use, is the subject of one or more issued or pending U.S. Patents (and foreign equivalents) owned or controlled by Umicore PMC. The purchase of this product from Umicore PMC through Sigma-Aldrich, its affiliates or their authorized distributors conveys to the buyer a limited, one-time, non-exclusive, non-transferable, non-assignable license. Buyer′s use of this product may infringe patents owned or controlled by third parties. It is the sole responsibility of buyer to ensure that its use of the product does not infringe the patent rights of third parties or exceed the scope of the license granted herein.

For any further information on product please refer to your local Umicore PMC contact at http://www.pmc.umicore.com
Grubbs Catalyst is a registered trademark of Umicore AG & Co. KG

Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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