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Merck
CN

75490

DL-Ornithine monohydrochloride

≥99.0% (AT)

Synonym(s):

(±)-2,5-Diaminopentanoic acid monohydrochloride

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About This Item

Linear Formula:
NH2(CH2)3CH(CO2H)(NH2) · HCl
CAS Number:
Molecular Weight:
168.62
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-956-0
Beilstein/REAXYS Number:
4153338
MDL number:
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Quality Level

assay

≥99.0% (AT)

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

~233 °C (dec.)

application(s)

peptide synthesis

SMILES string

Cl.NCCCC(N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H

InChI key

GGTYBZJRPHEQDG-UHFFFAOYSA-N

Application

DL-Ornithine monohydrochloride may be used as a starting material in the synthesis of (-)-(1-2H)putrescine dihydrochloride via enzymatic decarboxylation.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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The Stereochemistry of the Enzymic Decarboxylation of l-Arginine and of l-Ornithine
Richards JC and Spenser ID
Canadian Journal of Chemistry, 60(22), 2810-2820 (1982)
Juan C Marini et al.
American journal of physiology. Endocrinology and metabolism, 303(11), E1348-E1353 (2012-10-18)
Citrulline is an amino acid synthesized in the gut and utilized for the synthesis of the conditionally essential amino acid arginine. Recently, the origin of the ornithine utilized for citrulline synthesis has become a matter of discussion. Multiple physiological factors
Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming



Global Trade Item Number

SKUGTIN
87462-1G04061825936543
87462-5G04061832720296
75490-10G04061832596303
75490-50G04061832596310