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772453

Fmoc-Lys(palmitoyl)-OH

Name: Fmoc-Lys(palmitoyl)-OH
Brand: ALDRICH

95%

Synonym(s):

Palmitoyl lysine

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About This Item

Empirical Formula (Hill Notation):

C₃₇H₅₄N₂O₅

CAS Number:

1301706-55-7

Molecular Weight:

606.84

NACRES:

NA.26

PubChem Substance ID:

329767567

UNSPSC Code:

12352209

MDL number:

MFCD08274507

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Properties

Quality Level

100

assay

95%

form

powder or crystals

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

71-83 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCC(=O)NCCCC[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C37H54N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-26-35(40)38-27-20-19-25-34(36(41)42)39-37(43)44-28-33-31-23-17-15-21-29(31)30-22-16-18-24-32(30)33/h15-18,21-24,33-34H,2-14,19-20,25-28H2,1H3,(H,38,40)(H,39,43)(H,41,42)/t34-/m1/s1

InChI key

DQZCUQJUXKWZEE-UUWRZZSWSA-N

Description

Application

Amino acid-lipid conjugate for the solid phase synthesis of peptide-lipids. Lipidated peptides have been shown in some cases to lead to increased cellular permeability and metabolic stability.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

MKCM9785

MKBN8440V

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Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of alpha-conotoxin MII.

Joanne T Blanchfield et al.

Journal of medicinal chemistry, 46(7), 1266-1272 (2003-03-21)

The alpha-conotoxin MII is a two disulfide bridge containing, 16 amino acid long peptide toxin isolated from the marine snail Conus magus. This toxin has been found to be a highly selective and potent inhibitor of neuronal nicotinic acetylcholine receptors

Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities.

Grzegorz Bulaj et al.

Journal of medicinal chemistry, 51(24), 8038-8047 (2008-12-05)

Galanin is an endogenous neuropeptide that modulates seizures in the brain. Because this neuropeptide does not penetrate the blood-brain barrier, we designed truncated galanin analogues in which nonessential amino acid residues were replaced by cationic and/or lipoamino acid residues. The

Global Trade Item Number

SKU	GTIN
772453-1G	04061826654750
772453-5G	04061833340691