857246
p-Bromo-DL-phenylalanine
99%
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About This Item
Linear Formula:
BrC6H4CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
244.09
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
NACRES:
NA.22
EC Number:
237-941-3
MDL number:
InChI
1S/C9H10BrNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChI key
PEMUHKUIQHFMTH-UHFFFAOYSA-N
SMILES string
NC(Cc1ccc(Br)cc1)C(O)=O
assay
99%
form
powder
reaction suitability
reaction type: solution phase peptide synthesis
mp
262-263 °C (dec.) (lit.)
application(s)
peptide synthesis
storage temp.
2-8°C
Quality Level
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Thermal neutron capture therapy: the Japanese-Australian clinical trial for malignant melanoma.
B J Allen et al.
Basic life sciences, 50, 69-73 (1989-01-01)
Inchan Kwon et al.
Journal of the American Chemical Society, 128(36), 11778-11783 (2006-09-07)
Introduction of a yeast suppressor tRNA (ytRNA(Phe)(CUA)) and a mutant yeast phenylalanyl-tRNA synthetase (yPheRS (T415G)) into an Escherichia coli expression host allows in vivo incorporation of phenylalanine analogues into recombinant proteins in response to amber stop codons. However, high-fidelity incorporation
Neutron capture therapy for melanoma.
J A Coderre et al.
Basic life sciences, 50, 219-232 (1989-01-01)
Dose fractionation in neutron capture therapy for malignant melanoma.
B J Allen et al.
Basic life sciences, 50, 63-67 (1989-01-01)
M Ibba et al.
FEBS letters, 364(3), 272-275 (1995-05-15)
It has previously been demonstrated that the unnatural amino acid p-Cl-phenylalanine can be attached to tRNA(Phe) by a modified phenylalanyl-tRNA synthetase with relaxed amino acid substrate specificity. We show that this modification to the translational machinery of Escherichia coli is
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