900914
Methyltetrazine-NHS ester
≥95%
别名:
2,5-Dioxo-1-pyrrolidinyl 4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzeneacetate
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关于此项目
经验公式（希尔记法）:
C15H13N5O4
化学文摘社编号:
分子量:
327.29
UNSPSC Code:
12352108
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
powder or crystals
Quality Segment
assay
≥95%
form
powder or crystals
reaction suitability
reaction type: click chemistry, reagent type: cross-linking reagent
functional group
NHS ester
storage temp.
−20°C
SMILES string
O=C(ON1C(CCC1=O)=O)CC(C=C2)=CC=C2C3=NN=C(C)N=N3
InChI
1S/C15H13N5O4/c1-9-16-18-15(19-17-9)11-4-2-10(3-5-11)8-14(23)24-20-12(21)6-7-13(20)22/h2-5H,6-8H2,1H3
InChI key
BIHJLZOOHNOUCG-UHFFFAOYSA-N
Application
Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable