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91917

5,5,5-Trifluoro-DL-leucine

≥98.0% (sum of isomers, HPLC)

Synonym(s):

(±)-2-Amino-4-(trifluoromethyl)pentanoic acid

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About This Item

Empirical Formula (Hill Notation):
C6H10F3NO2
CAS Number:
2792-72-5
Molecular Weight:
185.14
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
329770097
NACRES:
NA.22
MDL number:
MFCD00039528
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Quality Segment

100

assay

≥98.0% (sum of isomers, HPLC)

form

crystals

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis

SMILES string

CC(CC(N)C(O)=O)C(F)(F)F

InChI

1S/C6H10F3NO2/c1-3(6(7,8)9)2-4(10)5(11)12/h3-4H,2,10H2,1H3,(H,11,12)

InChI key

XFGVJLGVINCWDP-UHFFFAOYSA-N

General description

5,5,5-Trifluoro-DL-leucine, also known as trifluoroleucine, is an analog of L-leucine amino acid, often used to synthesize highly fluorinated peptides.

Application

5,5,5-trifluoroleucine can be incorporated into the coiled-coil peptides to increase their thermal stability.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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