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Merck
CN

91917

5,5,5-三氟-DL-亮氨酸

≥98.0% (sum of isomers, HPLC)

别名:

(±)2-氨基-4-(三氟甲基)戊酸

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关于此项目

经验公式(希尔记法):
C6H10F3NO2
化学文摘社编号:
分子量:
185.14
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22
MDL number:
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Quality Level

assay

≥98.0% (sum of isomers, HPLC)

form

crystals

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis

SMILES string

CC(CC(N)C(O)=O)C(F)(F)F

InChI

1S/C6H10F3NO2/c1-3(6(7,8)9)2-4(10)5(11)12/h3-4H,2,10H2,1H3,(H,11,12)

InChI key

XFGVJLGVINCWDP-UHFFFAOYSA-N

General description

5,5,5-Trifluoro-DL-leucine, also known as trifluoroleucine, is an analog of L-leucine amino acid, often used to synthesize highly fluorinated peptides.

Application

5,5,5-trifluoroleucine can be incorporated into the coiled-coil peptides to increase their thermal stability.


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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I Bardazzi et al.
Folia microbiologica, 49(5), 534-538 (2005-02-11)
Two new plasmids, pEC3 and pECkan, were constructed and their use in yeast transformation described. Both plasmids are derivative of the pRS416 vector, in which the URA3 auxotrophic marker was replaced by the LEU4* gene (pEC3) or the kanMX4 gene
A coiled coil with a fluorous core
B Bilgicer
Journal of the American Chemical Society, 19, 4393-4399 (2001)
J T Mulligan et al.
Journal of bacteriology, 151(2), 609-619 (1982-08-01)
Fusions of the lac genes to the promoters of four structural genes in the methionine biosynthetic pathway, metA, metB, metE, and metF, were obtained by the use of the Mu d(Ap lac) bacteriophage. The levels of beta-galactosidase in these strains



全球贸易项目编号

货号GTIN
05-23-0300-1MG04055977206951
91917-500MG-F04061832596747