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A10809

4′-Hydroxy-3′-methoxyacetophenone

Name: 4′-Hydroxy-3′-methoxyacetophenone
Brand: ALDRICH

98%

Synonym(s):

Acetovanillone, Apocynin

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About This Item

Linear Formula:

HOC₆H₃(OCH₃)COCH₃

CAS Number:

498-02-2

Molecular Weight:

166.17

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24890503

EC Number:

207-854-5

Beilstein/REAXYS Number:

637373

MDL number:

MFCD00008747

Assay:

98%

Form:

powder

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Properties

Quality Level

100

assay

98%

form

powder

bp

263-265 °C/17 mmHg (lit.)

mp

112-115 °C (lit.)

SMILES string

COc1cc(ccc1O)C(C)=O

InChI

1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3

InChI key

DFYRUELUNQRZTB-UHFFFAOYSA-N

Description

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties.

Elham Khanicheh et al.

Arteriosclerosis, thrombosis, and vascular biology, 33(9), 2187-2192 (2013-08-03)

Antioxidative drugs continue to be developed for the treatment of atherosclerosis. Apocynin is an nicotinamide adenine dinucleotide phosphate oxidase inhibitor with anti-inflammatory properties. We used contrast-enhanced ultrasound molecular imaging to assess whether short-term apocynin therapy in atherosclerosis reduces vascular oxidative

Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase.

Jingfei Zhang et al.

Neuron, 82(1), 195-207 (2014-03-19)

Complement receptor 3 (CR3) activation in microglia is involved in neuroinflammation-related brain disorders and pruning of neuronal synapses. Hypoxia, often observed together with neuroinflammation in brain trauma, stroke, and neurodegenerative diseases, is thought to exacerbate inflammatory responses and synergistically enhance brain

Galectin-3, a biomarker linking oxidative stress and inflammation with the clinical outcomes of patients with atherothrombosis.

Julio Madrigal-Matute et al.

Journal of the American Heart Association, 3(4) (2014-08-07)

Galectin-3 (Gal-3) participates in different mechanisms involved in atherothrombosis, such as inflammation, proliferation, or macrophage chemotaxis. Thus, there have been committed intensive efforts to elucidate the function of Gal-3 in cardiovascular (CV) diseases. The role of Gal-3 as a circulating

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Global Trade Item Number

SKU	GTIN
A10809-25G	04061833334928
A10809-100G	04061831823516