C91492
Cyanogen bromide
reagent grade, 97%
Synonym(s):
Bromine cyanide
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About This Item
Linear Formula:
BrCN
CAS Number:
Molecular Weight:
105.92
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-051-2
Beilstein/REAXYS Number:
1697296
MDL number:
Assay:
97%
Form:
crystals
grade
reagent grade
Quality Level
vapor density
3.65 (vs air)
vapor pressure
100 mmHg ( 22.6 °C)
assay
97%
form
crystals
bp
61-62 °C (lit.)
mp
50-53 °C (lit.)
storage temp.
2-8°C
SMILES string
BrC#N
InChI
1S/CBrN/c2-1-3
InChI key
ATDGTVJJHBUTRL-UHFFFAOYSA-N
General description
Cyanogen bromide (CNBr) is a halogen halide. Its utility as a condensing agent during chemical ligation of oligodeoxyribonucleotides has been reported. Its threshold photoelectron (TPE) spectrum has been recorded under high resolution. The cryopolymerization of CNBr on irradiation has been investigated.
Application
Cyanogen bromide may be used:
- To activate polysaccharides for coupling with erythrocytes.
- As an oxidizing agent in urine thaimine assay.
- In the preparation of 2-amino-5-(2′-thienyl)-1,3,4-oxadiazole.
For peptide cleavage and use in protein immobilization procedures. Reaction with C60Ph5Cl produces a novel phenylated isoquinolino[3′,4′:1,2][60]fullerene.
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signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B
supp_hazards
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
>149.0 °F - closed cup
flash_point_c
> 65 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges
Regulatory Information
危险化学品
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Applied Biochemistry and Biotechnology, 44, 135-135 (1994)
Org. Mass Spectrom., 28, 1395-1395 (1993)
N I Sokolova et al.
FEBS letters, 232(1), 153-155 (1988-05-09)
Cyanogen bromide was found to condense oligodeoxyribonucleotides on a complementary template in aqueous solution. Optimum conditions for this vigorous and effective reaction were developed. CNBr proved to be useful for incorporation of phosphoramidate or pyrophosphate internucleotide bonds in DNA duplexes.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C91492-5G | 04061833523247 |
| C91492-100G | 04061833523216 |
| C91492-500G | 04061833523230 |
| C91492-25G | 04061833523223 |