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Merck
CN

D103705

Diglycolic anhydride

technical grade, 90%

Synonym(s):

1,4-Dioxane-2,6-dione

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About This Item

Empirical Formula (Hill Notation):
C4H4O4
CAS Number:
Molecular Weight:
116.07
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
224-761-5
Beilstein/REAXYS Number:
112527
MDL number:
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grade

technical grade

Quality Level

assay

90%

form

crystals

bp

240-241 °C (lit.)

mp

92-93 °C (lit.)

SMILES string

O=C1COCC(=O)O1

InChI

1S/C4H4O4/c5-3-1-7-2-4(6)8-3/h1-2H2

InChI key

PIYNUZCGMLCXKJ-UHFFFAOYSA-N

General description

Diglycolic anhydride (DGA) is derived from diglycolic acid, known for its ability to form polyesters and polyamides. DGA exhibits a low molecular weight and a high reactivity with hydroxyl and amine groups, making it a valuable intermediate in polymer chemistry. It can facilitate the formation of cross-linked networks, improving the mechanical properties of the resulting polymer.

Application

Diglycolic anhydride can be used:
  • As a building block to synthesize bio-based polyester and poly(ester amide)s with excellent thermal stability and good solubility in organic solvents.
  • To functionalize polyethylene terephthalate(PET) nanofibers for rare earth elements recovery. The addition of DGA enhances metal adsorption due to its rapid binding kinetics and high selectivity for recovering rare earth elements ions from aqueous solutions.
  • As a precursor to fabricate degradable polyester network coatings for medical devices to prevent biofouling of surfaces.


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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Jing-Min Liu et al.
Journal of hazardous materials, 344, 220-229 (2017-10-19)
Herein, for the first time, the typical porous Covalent Organic Frameworks (COFs) CTpBD with superior chemical stability and large surface area were applied as sorbents for solid phase extraction of trace ions via flow injection followed by inductively coupled plasma
Daniele Vinciguerra et al.
Journal of controlled release : official journal of the Controlled Release Society, 295, 223-236 (2019-01-07)
Well-defined, heterotelechelic polymer prodrugs for combination therapy were synthesized by using a combination of the "drug-initiated" nitroxide-mediated polymerization from a gemcitabine-alkoxyamine initiator and the nitroxide exchange reaction using TEMPO-bearing drugs to end-cap the drug-polymer chain-end by a second drug. This
Ying Gu et al.
Biosensors & bioelectronics, 128, 129-136 (2019-01-19)
For the determination of dopamine (DA) in serum samples, a quenching-type electrochemiluminescence sensor (MIECLS) was constructed in this study. Upconversion nanoparticles (UCNPs) enhanced by covalent organic frameworks (COFs)-based hybrid and oligoaniline-crosslinked gold nanoparticles (AuNPs) imprinting recognition sites were introduced in



Global Trade Item Number

SKUGTIN
D103705-25G04061833014875
D103705-100G04061833014868
D103705-5G04061833014882