E152
Epiboxidine hydrochloride
Synonym(s):
exo-2-(3-Methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C10H14N2O · HCl
CAS Number:
Molecular Weight:
214.69
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
color
yellow
solubility
H2O: 22 mg/mL
storage temp.
−20°C
SMILES string
Cl.Cc1cc(on1)[C@H]2C[C@@H]3CC[C@H]2N3
InChI
1S/C10H14N2O.ClH/c1-6-4-10(13-12-6)8-5-7-2-3-9(8)11-7;/h4,7-9,11H,2-3,5H2,1H3;1H/t7-,8-,9+;/m0./s1
InChI key
NSMIYECGCNTSSS-CTERPIQNSA-N
Biochem/physiol Actions
Potent nicotinic acetylcholine receptor agonist; analog of epibatidine
Disclaimer
Hygroscopic
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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B Badio et al.
European journal of pharmacology, 321(2), 189-194 (1997-02-26)
Synthetic (+/-)-epiboxidine (exo-2-(3-methyl-5-isoxazolyl)-7-azabicyclo[2.2.1]heptane) is a methylisoxazole analog of the alkaloid epibatidine, itself a potent nicotinic receptor agonist with antinociceptive activity. Epiboxidine contains a methylisoxazolyl ring replacing the chloropyridinyl ring of epibatidine. Thus, it is also an analog of another nicotinic
Manuel Tsiang et al.
Biochemistry, 50(10), 1567-1581 (2011-01-13)
We have developed a homogeneous time-resolved fluorescence resonance energy transfer (FRET)-based assay that detects the formation of HIV-1 integrase (IN) dimers. The assay utilizes IN monomers that express two different epitope tags that are recognized by their respective antibodies, coupled
Global Trade Item Number
| SKU | GTIN |
|---|---|
| E152-1MG | 04061826674628 |
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