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H33800

4-Hydroxy-2-mercapto-6-methylpyrimidine

Name: 4-Hydroxy-2-mercapto-6-methylpyrimidine
Brand: ALDRICH

95%

Synonym(s):

6-Methyl-2-thiouracil, 4-Hydroxy-2-mercapto 6-methylpyrimidine, MZU

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About This Item

Empirical Formula (Hill Notation):

C₅H₆N₂OS

CAS Number:

56-04-2

Molecular Weight:

142.18

EC Number:

200-252-3

UNSPSC Code:

12352100

PubChem Substance ID:

24895573

Beilstein/REAXYS Number:

115648

MDL number:

MFCD00006040

Assay:

95%

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Properties

assay

95%

mp

~330 °C (dec.) (lit.)

SMILES string

CC1=CC(=O)NC(=S)N1

InChI

1S/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)

InChI key

HWGBHCRJGXAGEU-UHFFFAOYSA-N

Description

pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Rapid and high-performance analysis of thyreostatic drug residues in urine using gas chromatography-mass spectrometry.

P Batjoens et al.

Journal of chromatography. A, 750(1-2), 127-132 (1996-10-25)

A more sensitive method was developed using the hyphenated technique of gas chromatography-mass spectrometry (GC-MS) supplementary to the official high-performance thin-layer chromatography (HPTLC) method. Even combined with less efficient extraction and clean-up methods, GC-MS is able to lower the detection

Homocysteine induced arteriosclerosis-like alterations of the aorta in normotensive and hypertensive rats following application of high doses of methionine.

D Matthias et al.

Atherosclerosis, 122(2), 201-216 (1996-05-01)

Following oral administration of methionine in high doses to normotensive (NR) and spontaneously hypertensive (SHR) rats, its degradation product, homocysteine (HC), which is markedly elevated in serum, exerts an angiotoxic action directed to the aorta. This is accompanied by considerable

Synthesis and biological activity of modified thiopyrimidine nucleosides.

A M Attia et al.

Nucleosides & nucleotides, 18(10), 2307-2315 (2000-01-05)

N3-beta-D-glucopyranosyl, galactopyranosyl and xylopyranosyl 6-methyl-2-methylthiouracil and their 5-bromo derivatives have been synthesized by coupling an alpha-acetobromosugar with the corresponding thiouracil. The new modified thiouridine analogues were evaluated for their inhibitory activity against Human Immunodeficiency Virus (HIV) replication in MT-4 cells

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