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Merck
CN

H4625

Hexachlorophene

crystalline

Synonym(s):

2,2′-Methylenebis(3,4,6-trichlorophenol)

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About This Item

Linear Formula:
CH2[C6H(Cl)3OH]2
CAS Number:
70-30-4
Molecular Weight:
406.90
EC Number:
200-733-8
UNSPSC Code:
12352100
PubChem Substance ID:
24895645
Beilstein/REAXYS Number:
2064407
MDL number:
MFCD00002171

Key Documents

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form

crystalline

color

off-white to tan

mp

163-165 °C (lit.)

SMILES string

Oc1c(Cl)cc(Cl)c(Cl)c1Cc2c(O)c(Cl)cc(Cl)c2Cl

InChI

1S/C13H6Cl6O2/c14-6-2-8(16)12(20)4(10(6)18)1-5-11(19)7(15)3-9(17)13(5)21/h2-3,20-21H,1H2

InChI key

ACGUYXCXAPNIKK-UHFFFAOYSA-N

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pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
100F0285
053K3603
048F0807

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Seoyoung Park et al.
Molecular pharmacology, 70(3), 960-966 (2006-06-01)
Aberrant activation of Wnt/beta-catenin signaling and subsequent up-regulation of beta-catenin response transcription (CRT) is a critical event in the development of human colon cancer. Thus, Wnt/beta-catenin signaling is an attractive target for the development of anticancer therapeutics. In this study
J P Hachem et al.
Dermatology (Basel, Switzerland), 202(4), 314-319 (2001-07-17)
Nickel (Ni) allergic contact dermatitis (ACD) alters the skin barrier. Our aim was to compare the efficacy of combination therapies on ACD, using a topical corticosteroid and a corneotherapy agent (barrier cream), with that of a single therapy with corticosteroids.
John M Boyce et al.
Infection control and hospital epidemiology, 23(12 Suppl), S3-40 (2003-01-08)
The Guideline for Hand Hygiene in Health-Care Settings provides health-care workers (HCWs) with a review of data regarding handwashing and hand antisepsis in health-care settings. In addition, it provides specific recommendations to promote improved hand-hygiene practices and reduce transmission of
Loren G Miller et al.
Antimicrobial agents and chemotherapy, 56(2), 1084-1086 (2011-11-16)
Recurrent community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infections are an increasingly common problem. However, there are no data on the efficacy of decolonization regimens. We prospectively evaluated 31 patients with recurrent CA-MRSA skin infections who received nasal mupirocin, topical hexachlorophene
Bernd Hutter et al.
Antimicrobial agents and chemotherapy, 48(8), 2838-2844 (2004-07-27)
We have generated a database of expression profiles carrying the transcriptional responses of the model organism Bacillus subtilis following treatment with 37 well-characterized antibacterial compounds of different classes. The database was used to build a predictor for the assignment of
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