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Merck
CN

P26406

2-Phenyl-1,3-indandione

97%

Synonym(s):

2-Phenyl-1H-indene-1,3(2H)-dione, Phenindione

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About This Item

Empirical Formula (Hill Notation):
C15H10O2
CAS Number:
83-12-5
Molecular Weight:
222.24
EC Number:
201-454-4
UNSPSC Code:
12352100
PubChem Substance ID:
24898344
Beilstein/REAXYS Number:
1911699
MDL number:
MFCD00003782
Assay:
97%
Form:
crystals

Key Documents

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assay

97%

form

crystals

mp

144-148 °C (lit.)

SMILES string

O=C1C(c2ccccc2)C(=O)c3ccccc13

InChI

1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H

InChI key

NFBAXHOPROOJAW-UHFFFAOYSA-N

Gene Information

human ... VKORC1(79001)

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H317

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
14926CQ
09923CW

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P Gelot et al.
Annales de dermatologie et de venereologie, 139(4), 282-286 (2012-04-10)
Antiphospholipid syndrome (APS) is characterised by arterial or venous thrombosis combined with the presence of specific antibodies known as antiphospholipids. It is commonly associated with cutaneous signs. Herein we report a case of atypical cutaneous eruption occurring during the course
Gérard Cam et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(4), 1554-1558 (2011-09-21)
Among the vitamin K antagonists (VKA), indanedione-derived VKA is suspected to induce an immunoallergic risk. One indanedione-derived VKA, fluindione, is still being used in France. The aim of this study was to evaluate the contribution of VKA to acute and
Amélie Daveluy et al.
European journal of clinical pharmacology, 68(1), 101-105 (2011-07-28)
Fluindione is an oral vitamin K antagonist (indanedione derivative) exclusively marketed in France and Luxembourg, known to have immuno-allergic adverse effects such as hepatitis, fever or interstitial nephritis. A few cases of drug reaction with eosinophilia and systemic symptoms (DRESS)
Eric Pautas et al.
Geriatrie et psychologie neuropsychiatrie du vieillissement, 9(2), 171-177 (2011-06-22)
Vitamin K antagonist tablets are often split to fractionate the dose by elderly patients. We performed a study in order to assess the divisibility of one dosage strength of score-lined warfarin and of score-lined fluindione. Due to a recent change
C Merklen-Djafri et al.
Annales de dermatologie et de venereologie, 139(3), 199-203 (2012-03-10)
Cutaneous necrosis is a rare complication of vitamin K antagonist therapy. It presents as cutaneous hemorrhagic necrosis and usually occurs at the start of treatment. We describe an atypical case of recurrent skin necrosis after two years of treatment with
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