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Merck
CN

W304409

L-(+)-Tartaric acid

≥99.7%, FCC, FG

Synonym(s):

(2R,3R)-(+)-Tartaric acid, L-Threaric acid

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About This Item

Linear Formula:
HO2CCH(OH)CH(OH)CO2H
CAS Number:
87-69-4
Molecular Weight:
150.09
FEMA Number:
3044
Council of Europe no.:
18
UNSPSC Code:
12164502
PubChem Substance ID:
24901442
NACRES:
NA.21
EC Number:
201-766-0
Flavis number:
8.018
MDL number:
MFCD00064207
Beilstein/REAXYS Number:
1725147
Organoleptic:
odorless
Grade:
FG, Halal
Biological source:
synthetic
Agency:
meets purity specifications of JECFA
Food allergen:
no known allergens

Key Documents

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biological source

synthetic

Quality Level

300, 400

grade

FG, Halal

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 178/2002, FCC, FDA 21 CFR 163.110, FDA 21 CFR 163.111, FDA 21 CFR 163.112, FDA 21 CFR 184.1099

vapor density

5.18 (vs air)

assay

≥99.7%

form

crystalline powder

optical activity

[α]20/D +12.5°, c = 20 in H2O

autoignition temp.

797 °F

mp

170-172 °C (lit.)

solubility

water: soluble 150 g/L at 25 °C

cation traces

As: ≤3 ppm, Cd: ≤1 ppm, Hg: ≤1 ppm, heavy metals (as Pb): ≤2 ppm

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O

InChI

1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2-/m1/s1

InChI key

FEWJPZIEWOKRBE-JCYAYHJZSA-N

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General description

L-(+)-Tartaric acid is an organic acid commonly used as an acidulant, flavor enhancer, firming agent and humectant.

Application


  • Terahertz-spectroscopy for non-destructive determination of crystallinity of L-tartaric acid in smartFilms and tablets made from paper.: This study leverages terahertz spectroscopy to assess the crystallinity of L-(+)-tartaric acid in innovative pharmaceutical applications, enhancing non-destructive testing methods for quality control (Ornik et al., 2020 May). Link to the article.

  • Enhanced pulmonary absorption of poorly soluble itraconazole by micronized cocrystal dry powder formulations.: Research shows the use of L-(+)-tartaric acid in cocrystal formulations with itraconazole to improve its pulmonary absorption, demonstrating a significant advancement in drug delivery technologies (Karashima et al., 2017 Jun). Link to the article.

  • Physicochemical Evaluation and Developability Assessment of Co-amorphouses of Low Soluble Drugs and Comparison to the Co-crystals.: This article discusses the role of L-(+)-tartaric acid in enhancing the solubility and bioavailability of pharmaceuticals through co-amorphous systems, offering a critical insight into drug formulation strategies (Yamamoto et al., 2016 Dec). Link to the article.

  • Functionalized polycarbonate derived from tartaric acid: enzymatic ring-opening polymerization of a seven-membered cyclic carbonate.: This research explores the synthesis of biodegradable polymers from L-(+)-tartaric acid, emphasizing its utility in developing environmentally friendly materials (Wu et al., 2008 Oct). Link to the article.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT5006
SHBR4882
SHBQ3265
SHBP4508
SHBN6790

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Dictionary of Food Compounds with CD-ROM: Additives, Flavors, and Ingredients, 1794-1794 (2012)
Andrea Bencini et al.
Chemical communications (Cambridge, England), 48(84), 10428-10430 (2012-09-18)
A chiral ditopic polyammonium receptor featuring two [9]aneN(3) moieties separated by a (S)-BINOL linker is able to selectively bind and sense in water (S,S)-tartaric acid over its (R,R)/meso forms.
Mark D Eddleston et al.
Chemical communications (Cambridge, England), 48(92), 11340-11342 (2012-10-18)
The formation of diastereomeric cocrystals of malic acid and tartaric acid was investigated by liquid-assisted grinding in the solid state. We demonstrate that racemic malic acid can be converted into two distinct diastereomeric cocrystal phases by grinding with a single
J B Olivato et al.
Carbohydrate polymers, 92(2), 1705-1710 (2013-02-13)
Tartaric acid (TA), a dicarboxylic acid, can act as a compatibiliser in starch/polyester blends. A mixture design was proposed to evaluate the effect of TA on the properties of starch/poly (butylene adipate co-terephthalate) (PBAT) blown films plasticised with glycerol. The
Mrinal Kanti Bain et al.
Carbohydrate polymers, 91(2), 529-536 (2012-11-06)
Gelation temperature of MC was reduced from 59°C to 54°C with the addition of 10% PEG. Sodium tartrate (NaT) and sodium citrate (NaC) were added to the MC-PEG solution to further reduce the gelation temperature close to physiological temperature. Different
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Global Trade Item Number

SKUGTIN
W304409-SAMPLE04061837518638
W304409-1KG04061835566402
W304409-10KG04061835566396
W304409-5KG04061835566419

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