W424501
Trimethylamine N-oxide
98%
Synonym(s):
TMANO
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About This Item
Linear Formula:
(CH3)3N(O)
CAS Number:
Molecular Weight:
75.11
FEMA Number:
4245
Flavis number:
11.025
EC Number:
214-675-6
MDL number:
biological source
synthetic
assay
98%
mp
220-222 °C (lit.)
organoleptic
fishy
SMILES string
C[N+](C)(C)[O-]
InChI
1S/C3H9NO/c1-4(2,3)5/h1-3H3
InChI key
UYPYRKYUKCHHIB-UHFFFAOYSA-N
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Allan Chris M Ferreon et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(44), 17826-17831 (2012-07-25)
Protein structure and function depend on a close interplay between intrinsic folding energy landscapes and the chemistry of the protein environment. Osmolytes are small-molecule compounds that can act as chemical chaperones by altering the environment in a cellular context. Despite
Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy.
Sergey Lupachyk et al.
Diabetes, 62(3), 944-952 (2013-02-01)
Endoplasmic reticulum stress resulting from abnormal folding of newly synthesized proteins impairs metabolism, transcriptional regulation, and gene expression, and it is a key mechanism of cell injury. Endoplasmic reticulum stress plays an important role in cardiovascular and neurodegenerative diseases, cancer
Zeneng Wang et al.
Nature, 472(7341), 57-63 (2011-04-09)
Metabolomics studies hold promise for the discovery of pathways linked to disease processes. Cardiovascular disease (CVD) represents the leading cause of death and morbidity worldwide. Here we used a metabolomics approach to generate unbiased small-molecule metabolic profiles in plasma that