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Merck
CN

C7206

Z-Gly-OH

99%

Synonym(s):

Z-Glycine

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About This Item

Linear Formula:
C6H5CH2OOCNHCH2COOH
CAS Number:
Molecular Weight:
209.20
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
214-516-0
MDL number:
Beilstein/REAXYS Number:
526877
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Quality Level

assay

99%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

color

beige

mp

118-122 °C (lit.)

application(s)

peptide synthesis

SMILES string

OC(=O)CNC(=O)OCc1ccccc1

InChI

1S/C10H11NO4/c12-9(13)6-11-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)

InChI key

CJUMAFVKTCBCJK-UHFFFAOYSA-N

General description

Z-Gly-OH, also known as N-benzyloxycarbonylglycine, is an amino acid widely used in solution phase peptide synthesis.

Application

Z-Gly-OH is a versatile reagent that can be used to synthesize a variety of compounds such as:
  • glycine-derived peptides like Z-Gly-DL-Ala-OBzl and Z-Gly-L-Ala-OBzl
  • glycine N-substituted amides such as glycine-N-methylamide hydrochloride and glycine-N-isopropylamide hydrochloride


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Studies on Separation of Amino Acids and Related Compounds. V. A Racemization Test in Peptide Synthesis by the Use of an Amino Acid Analyzer
Bulletin of the Chemical Society of Japan, 44, 3391-3395 (1971)
Formation of peptide bonds in the coordination sphere of cobalt (III)
Journal of the American Chemical Society, 89, 6096-6103 (1967)
Duality of mechanism in the tetramethylfluoroformamidinium hexafluorophosphate-mediated synthesis of N-benzyloxycarbonylamino acid fluorides.
R Fiammengo et al.
The Journal of organic chemistry, 66(17), 5905-5910 (2001-08-21)



Global Trade Item Number

SKUGTIN
C7206-100G04061838353283
C7206-500G04061838353306
C7206-25G04061838353290