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D106208

Sigma-Aldrich

3,4-Dihydro-2H-pyran

97%

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Synonym(s):
2,3,4-Trihydropyran, 2H-3,4-Dihydropyran, Dihydro-2H-pyran, Dihydropyran
Empirical Formula (Hill Notation):
C5H8O
CAS Number:
Molecular Weight:
84.12
Beilstein:
103493
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor density

2.9 (vs air)

Quality Level

Assay

97%

form

liquid

refractive index

n20/D 1.440 (lit.)

bp

86 °C (lit.)

mp

−70 °C (lit.)

density

0.922 g/mL at 25 °C (lit.)

SMILES string

C1COC=CC1

InChI

1S/C5H8O/c1-2-4-6-5-3-1/h2,4H,1,3,5H2

InChI key

BUDQDWGNQVEFAC-UHFFFAOYSA-N

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This Item
8.02971711357669210
3,4-Dihydro-2H-pyran 97%

Sigma-Aldrich

D106208

3,4-Dihydro-2H-pyran

3,4-Dihydro-2H-pyran for synthesis

Sigma-Aldrich

8.02971

3,4-Dihydro-2H-pyran

form

liquid

form

liquid

form

liquid

form

-

refractive index

n20/D 1.440 (lit.)

refractive index

-

refractive index

n20/D 1.463

refractive index

n20/D 1.534

bp

86 °C (lit.)

bp

85.5 °C/1013 hPa

bp

-

bp

-

mp

−70 °C (lit.)

mp

-70 °C

mp

-

mp

-

density

0.922 g/mL at 25 °C (lit.)

density

0.929 g/cm3 at 20 °C

density

0.977 g/cm3 at 25 °C

density

1.109 g/mL at 25 °C

Application

3,4-Dihydro-2H-pyran can be used as a reactant to synthesize:
  • Tetrahydropyranylated product from alcohols in the presence of phenolsulfonic acid-formaldehyde resin catalyst.
  • Tetrahydropyran derivatives by reacting pyrazoles in the presence of trifluoroacetic acid.
  • 1,2,3,4-Tetrahydroquinoline derivatives by cation-exchange resin catalyzed Domino reaction with aromatic amines.
  • Tetrahydroquinolines from aryl azides in the presence of FeCl3-NaI.

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - Skin Sens. 1B

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

5.0 °F - closed cup

Flash Point(C)

-15 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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Domino reaction of anilines with 3, 4-dihydro-2H-pyran catalyzed by cation-exchange resin in water: an efficient synthesis of 1, 2, 3, 4-tetrahydroquinoline derivatives
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