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F5062

Fmoc-Lys(Me)3-OH Chloride

≥97%, for peptide synthesis

Synonym(s):

Fmoc-Lys(Me3Cl)-OH, N-alpha-Fmoc-N-alpha-trimethyl-N-L-lysine · chloride

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About This Item

Empirical Formula (Hill Notation):
C24H31ClN2O4
CAS Number:
201004-29-7
Molecular Weight:
446.97
MDL number:
MFCD00672333
UNSPSC Code:
12352209
NACRES:
NA.26
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Product Name

Fmoc-Lys(Me)3-OH Chloride, ≥97%

Quality Segment

assay

≥97%

form

liquid

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

shipped in

dry ice

storage temp.

−20°C

SMILES string

Cl.[N+](CCCC[C@H](N=C([O-])OCC1c2c(cccc2)c3c1cccc3)C(=O)O)(C)(C)C

InChI

1S/C24H30N2O4.ClH/c1-26(2,3)15-9-8-14-22(23(27)28)25-24(29)30-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21;/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H-,25,27,28,29);1H/t22-;/m0./s1

InChI key

XUJRNPVABVHOAJ-FTBISJDPSA-N

General description

Fmoc protected N-trimethyl lysine

Application

Fmoc-Lys(Me)3-OH chloride is one of the common N-terminal protected reagents used in the peptide synthesis. Some of the reported examples are:
  • Synthesis of peptide linkers for monoclonal antibody-auristatin F conjugates.
  • Preparation of multifunctional reagents with enhanced ionization properties for the analysis of protein modification in human cells and dynamic profiling of protein lipidation.
  • Sequential peptide ligation to synthesize histone H3 containing a trimethyl lysine residue, with modified tail region.

Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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