F5062
Fmoc-Lys(Me)3-OH Chloride
≥97%, for peptide synthesis
Synonym(s):
Fmoc-Lys(Me3Cl)-OH, N-alpha-Fmoc-N-alpha-trimethyl-N-L-lysine · chloride
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About This Item
Empirical Formula (Hill Notation):
C24H31ClN2O4
CAS Number:
Molecular Weight:
446.97
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.26
Product Name
Fmoc-Lys(Me)3-OH Chloride, ≥97%
Quality Segment
assay
≥97%
form
liquid
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
application(s)
peptide synthesis
functional group
Fmoc
shipped in
dry ice
storage temp.
−20°C
SMILES string
Cl.[N+](CCCC[C@H](N=C([O-])OCC1c2c(cccc2)c3c1cccc3)C(=O)O)(C)(C)C
InChI
1S/C24H30N2O4.ClH/c1-26(2,3)15-9-8-14-22(23(27)28)25-24(29)30-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21;/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H-,25,27,28,29);1H/t22-;/m0./s1
InChI key
XUJRNPVABVHOAJ-FTBISJDPSA-N
General description
Fmoc protected N-trimethyl lysine
Application
Fmoc-Lys(Me)3-OH chloride is one of the common N-terminal protected reagents used in the peptide synthesis. Some of the reported examples are:
- Synthesis of peptide linkers for monoclonal antibody-auristatin F conjugates.
- Preparation of multifunctional reagents with enhanced ionization properties for the analysis of protein modification in human cells and dynamic profiling of protein lipidation.
- Sequential peptide ligation to synthesize histone H3 containing a trimethyl lysine residue, with modified tail region.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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