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Merck
CN

P42800

2-Picolinic acid

ReagentPlus®, 99%

Synonym(s):

Pyridine-2-carboxylic acid, α-Picolinic acid

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About This Item

Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
Molecular Weight:
123.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-719-7
Beilstein/REAXYS Number:
109595
MDL number:
Assay:
99%
Form:
crystals
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Product Name

2-Picolinic acid, ReagentPlus®, 99%

InChI key

SIOXPEMLGUPBBT-UHFFFAOYSA-N

InChI

1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)

SMILES string

OC(=O)c1ccccn1

product line

ReagentPlus®

assay

99%

form

crystals

reaction suitability

reagent type: catalyst
reagent type: ligand
reaction type: C-H Activation

mp

139-142 °C (lit.)

functional group

carboxylic acid

Quality Level

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Application

Chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Orient. J. Chem., 9, 43-43 (1993)
Transition Met. Chem. (London), 19, 521-521 (1994)
Bhuvaneshwari Sundaram et al.
BioFactors (Oxford, England), 38(1), 59-68 (2012-01-31)
Chromium has been recognized as an essential trace element that plays an important role in carbohydrate metabolism. However, the molecular mechanisms involved in its action are not clear. This study was undertaken to understand the mechanism of chromium action in
Lisheng Deng et al.
Journal of medicinal chemistry, 54(13), 4721-4734 (2011-05-13)
1-Deoxy-D-xylulose-5-phosphate reductoisomerase (DXR) is a novel target for developing new antibacterial (including antituberculosis) and antimalaria drugs. Forty-one lipophilic phosphonates, representing a new class of DXR inhibitors, were synthesized, among which 5-phenylpyridin-2-ylmethylphosphonic acid possesses the most activity against E. coli DXR
L Varesio et al.
Journal of immunology (Baltimore, Md. : 1950), 145(12), 4265-4271 (1990-12-15)
We have studied the effects of picolinic acid, a product of tryptophan degradation, on the activation of mouse peritoneal macrophages (M phi). Picolinic acid acts synergistically with IFN-gamma in activating M phi from C57BL/6 mice. Moreover, M phi from C3H/HeJ

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