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Merck
CN

1.04956

tri-Potassium citrate monohydrate

EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, FCC, E 332

Synonym(s):

tri-Potassium citrate monohydrate, Tripotassium citrate, Citric acid potassium salt, 2-Hydroxy-1,2,3-Propanetriccarboxylic Acid

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About This Item

Empirical Formula (Hill Notation):
C6H5K3O7 · xH2O
CAS Number:
Molecular Weight:
306.39 (anhydrous basis)
UNSPSC Code:
12352107
E Number:
E332
EC Index Number:
212-755-5
MDL number:
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Quality Level

agency

BP, Ph. Eur., USP

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

solid

pH

7.5-9.0 (20 °C, 50 g/L in H2O)

mp

>180 °C (Elimination of water of crystallisation)

density

1.98 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

SMILES string

[K+].[K+].[K+].[O-]C(=O)C(O)(CC(=O)[O-])CC(=O)[O-].O

InChI

1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3

InChI key

PJAHUDTUZRZBKM-UHFFFAOYSA-K

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Potassium citrate is typically used as buffering, alkalizing and sequestering agent. Additional uses include the application as potassium source and as therapeutic ingredient to treat cystitis by alkalizing the urine.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
104956902904022536946092
104956500004022536058085
104956100004022536058078
104956000104027269279912