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Merck
CN

1.06398

Sodium carbonate

anhydrous, EMPROVE® ESSENTIAL, Ph. Eur., BP, ChP, JP, NF

Synonym(s):

anhydrous soda, Calcined soda, Carbonic acid disodium salt, Soda ash

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About This Item

Linear Formula:
Na2CO3
CAS Number:
Molecular Weight:
105.99
EC Index Number:
207-838-8
UNSPSC Code:
12352302
Beilstein/REAXYS Number:
4154566
MDL number:
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Quality Level

agency

BP, ChP, JP, NF, Ph. Eur.

product line

EMPROVE® ESSENTIAL

form

solid

pH

11.16 (25 °C, 4 g/L in H2O)

mp

851 °C (lit.)

solubility

212.5 g/L

density

2.53 g/cm3 at 20 °C

application(s)

liquid formulation
pharmaceutical
solid formulation

storage temp.

2-25°C

SMILES string

O=C(O[Na])O[Na]

InChI

1S/CH2O3.2Na/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2

InChI key

CDBYLPFSWZWCQE-UHFFFAOYSA-L

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium carbonate is a commonly used ingredient in both food and pharmaceutics. In pharmaceutical applications, sodium carbonate is used as pH adjuster, or a source of carbon dioxide in oral formulations such as effervescent tablets or granules.

Biochem/physiol Actions

Buffer component, may be used for the removal of peripheral membrane proteins.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
B60428-1KG04061826004517
B60428-500G04061832675244
B60428-100G04061833434437
106398902904022536935690
106398905204022536983561
106398500004022536076065
106398000104027269279837
106398100004022536076041
106398901304027269174446