1.10110
2-[4-(2-Hydroxyethyl)-1-piperazinyl]-ethanesulfonic acid
HEPES EMPROVE® EXPERT
Synonym(s):
HEPES, 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid)
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About This Item
Quality Level
product line
EMPROVE® EXPERT
potency
>2000 mg/kg LD50, oral (Rat)
feature
RNase and DNase free
technique(s)
API processing | cocrystal formation: suitable
pH
5.0-5.5 (20 °C, 100 g/L in H2O)
useful pH range
6.8-8.2
pKa (25 °C)
7.5
mp
212.6 °C
solubility
703.6 g/L
density
1.44 g/cm3 at 20 °C
bulk density
560 kg/m3
storage temp.
2-25°C
SMILES string
OCCN1CCN(CC1)CCS(O)(=O)=O
InChI
1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
InChI key
JKMHFZQWWAIEOD-UHFFFAOYSA-N
General description
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Legal Information
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Articles
Instead of addressing API solubility during formulation, tackle it early during development. Read about the various methods for API processing.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 1101100003 | 04054839557477 |
| 1101100250 | 04022536121574 |
| 1101106010 | 04065270331205 |
| 1101109025 | 04022536513423 |
| 1101105000 | 04065272647106 |
| 1101106025 | 04054839364358 |
| 1101101000 | 04022536121581 |